Gene: AT1G47290 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G47290
Transcript Identifier
AT1G47290.2
Gene Type
Coding gene
Location
1 : 17336121-17339030 : positive

Family

Gene family
HOM03D002189
(79 genes in 31 species)
specific family
Subfamily
ORTHO03D002546
(41 genes in 30 species)
specific family

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Descriptions

Description
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
Curated Summary
Encodes an enzyme with 3β-hydroxysteroid dehydrogenase/C4-decarboxylase activity in vitro. The activity of the enzyme was determined using microsomal extracts of yeast overexpressing the Arabidopsis gene. Cytosolic fractions failed to be associated to the activity, leading to the speculation that the enzyme is membrane-bound.
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Identifiers

Identifier Name
alias3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 1
alias3BETAHSD/D1
aliasAT3BETAHSD/D1
uniprotQ9FX01

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006694ISS, IEAGene Ontologysteroid biosynthetic process1
GO:0006084RCAGene Ontologyacetyl-CoA metabolic process1
GO:0016126IEA, RCAUniProtsterol biosynthetic process1 2 3 4 5
GO:0016132RCAGene Ontologybrassinosteroid biosynthetic process1
GO:0019745RCAGene Ontologypentacyclic triterpenoid biosynthetic process1
GO:0055114IEAInterProoxidation-reduction process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003854IEA, ISSUniProt3-beta-hydroxy-delta5-steroid dehydrogenase activity1 2 3 4 5
GO:0047012IDA, IGI, UniProtsterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity1 2 3 4 5 6
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016020IDAUniProtmembrane1 2 3 4 5
GO:0005789IEAUniProtendoplasmic reticulum membrane1 2 3 4
GO:0016021IEAUniProtintegral to membrane1 2 3 4

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR0022253-beta hydroxysteroid dehydrogenase/isomerase
IPR016040NAD(P)-binding domain

Mapman id Description
11.8.4lipid metabolism.exotics (steroids, squalene etc).3-beta hydroxysteroid dehydrogenase/isomerase
No SignalP domains detected for this gene.