Gene: AT1G31360 (Arabidopsis thaliana)

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Gene Identifier
AT1G31360
Transcript Identifier
AT1G31360.1
Gene Type
Coding gene
Location
1 : 11232422-11237412 : positive

Family

Gene family
HOM03D000476
(268 genes in 30 species)
specific family
Subfamily
ORTHO03D007740
(31 genes in 28 species)
specific family

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Descriptions

Description
RECQ helicase L2
Curated Summary
Encodes a (d)NTP-dependent 3'->5' DNA helicase. This protein can also disrupt D loop structures and may mediate branch migration of Holliday junctions when tested in vitro. The unwinding activity of the enzyme depends on the presence of divalent cations (Mg2+, Mn2+, or Ca2+, but not Zn2+).(d)NTPs are also required with ATP and dATP supporting the greatest amount of DNA unwinding in vitro.
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Identifiers

Identifier Name
aliasRECQ helicase L2
aliasATRECQ2
aliasRECQL2
aliasARABIDOPSIS THALIANA RECQ 2
aliasMED34
uniprotQ9FT73

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006281IC, IEA, UniProtDNA repair1 2 3 4 5 6 7 8 9
GO:0006310IC, IEA, UniProtDNA recombination1 2 3 4 5 6 7 8 9
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0006396RCAGene OntologyRNA processing1
GO:0010413RCAGene Ontologyglucuronoxylan metabolic process1
GO:0045492RCAGene Ontologyxylan biosynthetic process1
GO:0006260IEAUniProtDNA replication1 2 3 4 5 6 7 8
GO:0044237IEAInterProcellular metabolic process
GO:0006355IEAUniProtregulation of transcription, DNA-dependent1 2 3 4 5 6 7 8
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008026ISS, IEAGene OntologyATP-dependent helicase activity1
GO:0005515IPIGene Ontologyprotein binding1
GO:0009378IDAUniProtfour-way junction helicase activity1 2 3 4 5 6 7 8 9
GO:0043138IDAUniProt3'-5' DNA helicase activity1 2 3 4 5 6 7 8 9
GO:0043140IEAUniProtATP-dependent 3'-5' DNA helicase activity1 2 3 4 5 6 7 8
GO:0000166IEAInterPronucleotide binding
GO:0004386IEAInterProhelicase activity
GO:0003824IEAInterProcatalytic activity
GO:0003676IEAInterPronucleic acid binding
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8
GO:0003677IEAUniProtDNA binding1 2 3 4 5 6 7 8
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8
GO:0042623IEAPLAZA HomologyATPase activity, coupledHOM03D000476
GO:0016887IEAPLAZA HomologyATPase activityHOM03D000476
GO:0070035IEAPLAZA Homologypurine NTP-dependent helicase activityHOM03D000476

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0016592IDAUniProtmediator complex1 2 3 4 5 6 7 8 9
GO:0005622IEAInterProintracellular

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001650Helicase, C-terminal
IPR002121HRDC domain
IPR011545DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001Helicase, superfamily 1/2, ATP-binding domain
IPR004589DNA helicase, ATP-dependent, RecQ type
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR010997HRDC-like
IPR011991Winged helix-turn-helix DNA-binding domain
IPR018982RQC domain

Mapman id Description
28.1DNA.synthesis/chromatin structure
No SignalP domains detected for this gene.