Gene: AT1G18450 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
1 : 6348199-6351766 : positive


Gene family
(622 genes in 31 species)
specific family
(34 genes in 27 species)
specific family
Duplication type
Block duplicate

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actin-related protein 4
Curated Summary
Encodes a gene similar to actin-related proteins in other organisms. Member of nuclear ARP family of genes. Component of chromatin remodeling complexes, involved in chromatin-mediated gene regulation. Phenotype of the arp4-1 mutant allele revealed partial sterility due to defects in anther development. Targeting the distinct, 3' UTR of AtARP4 transcripts with RNA interference caused a drastic reduction in the level of AtARP4 protein expression, and resulted in strong pleiotropic phenotypes such as altered organization of plant organs, early flowering, delayed flower senescence and high levels of sterility. Western blot analysis and immunolabelling demonstrated a clear correlation between reductions in the level of AtARP4 expression and severity of the phenotypes.
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Identifier Name
aliasactin-related protein 4





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006325TAS, RCAUniProtchromatin organization1 2 3 4 5 6 7 8
GO:0048235IMPUniProtpollen sperm cell differentiation1 2 3 4 5 6 7
GO:0048574IMPUniProtlong-day photoperiodism, flowering1 2 3 4 5 6 7
GO:0000003RCAGene Ontologyreproduction1
GO:0000398RCAGene OntologymRNA splicing, via spliceosome1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006312RCAGene Ontologymitotic recombination1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0006346RCAGene Ontologymethylation-dependent chromatin silencing1
GO:0007131RCAGene Ontologyreciprocal meiotic recombination1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009560RCAGene Ontologyembryo sac egg cell differentiation1
GO:0009616RCAGene Ontologyvirus induced gene silencing1
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009845RCAGene Ontologyseed germination1
GO:0009855RCAGene Ontologydetermination of bilateral symmetry1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0009933RCAGene Ontologymeristem structural organization1
GO:0010014RCAGene Ontologymeristem initiation1
GO:0010050RCAGene Ontologyvegetative phase change1
GO:0010073RCAGene Ontologymeristem maintenance1
GO:0010090RCAGene Ontologytrichome morphogenesis1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010182RCAGene Ontologysugar mediated signaling pathway1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010267RCAGene Ontologyproduction of ta-siRNAs involved in RNA interference1
GO:0010638RCAGene Ontologypositive regulation of organelle organization1
GO:0016246RCAGene OntologyRNA interference1
GO:0016567RCAGene Ontologyprotein ubiquitination1
GO:0016572RCAGene Ontologyhistone phosphorylation1
GO:0019915RCAGene Ontologylipid storage1
GO:0031048RCAGene Ontologychromatin silencing by small RNA1
GO:0033044RCAGene Ontologyregulation of chromosome organization1
GO:0035196RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1
GO:0048573RCAGene Ontologyphotoperiodism, flowering1
GO:0050826RCAGene Ontologyresponse to freezing1
GO:0051567RCAGene Ontologyhistone H3-K9 methylation1
GO:0016568IEAUniProtchromatin modification1 2 3 4 5 6
GO:0006996IEAPLAZA Homologyorganelle organizationHOM03D000164

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005200ISSUniProtstructural constituent of cytoskeleton1 2 3 4 5 6 7
GO:0005524IEAPLAZA HomologyATP bindingHOM03D000164

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737IEA, ISMUniProtcytoplasm1 2 3 4 5 6 7
GO:0005634IDAGene Ontologynucleus1
GO:0005730IDAUniProtnucleolus1 2 3 4 5 6 7
GO:0005856IEAUniProtcytoskeleton1 2 3 4 5 6

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004000Actin-related protein

Mapman id Description
No SignalP domains detected for this gene.