Gene: AT1G12550 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G12550
Transcript Identifier
AT1G12550.1
Gene Type
Coding gene
Location
1 : 4274649-4275831 : positive

Family

Gene family
HOM03D000694
(201 genes in 29 species)
specific family
Subfamily
ORTHO03D013102
(18 genes in 15 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
D-isomer specific 2-hydroxyacid dehydrogenase family protein
Curated Summary
Encodes a hydroxypyruvate reductase that reduces HP to glycerate and shows even more activity with glyoxylate, a more upstream intermediate of the photorespiratory cycle. It is likely targeted to the chloroplast where it could provide a compensatory bypass for the reduction of HP and glyoxylate within this compartment.
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Identifiers

Identifier Name
aliashydroxypyruvate reductase 3
aliasHPR3
uniprotQ9LE33

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009853IMPUniProtphotorespiration1 2 3
GO:0055114IDA, IEAGene Ontologyoxidation-reduction process1
GO:0008152IEAInterPrometabolic process
GO:0009854IEAUniProtoxidative photosynthetic carbon pathway1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016491ISSGene Ontologyoxidoreductase activity1
GO:0016618IDAUniProthydroxypyruvate reductase activity1 2 3
GO:0030267IDAUniProtglyoxylate reductase (NADP) activity1 2 3
GO:0048037IEAInterProcofactor binding
GO:0051287IEAUniProtNAD binding1 2
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016614IEAPLAZA Homologyoxidoreductase activity, acting on CH-OH group of donorsHOM03D000694

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR016040NAD(P)-binding domain

Mapman id Description
1.2.6PS.photorespiration.hydroxypyruvate reductase
No SignalP domains detected for this gene.