PLAZA 3.0 Dicots gene overview : AT1G12520

Gene: AT1G12520 (Arabidopsis thaliana)

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Curated Summary: Copper-zinc superoxide dismutase copper chaperone (delivers copper to the Cu-Zn superoxide dismutase). Localized to the chloroplast. Expressed in roots and shoots. Up-regulated in response to copper and senescence. The AtACC activates all three CuZnSOD activities located in three different subcellular compartments. Contains three domains, central, ATX-1 like and C-terminal. ATX-1 like domain essential for the copper chaperone function of AtCCS in planta.

GO term	Evidence(s)	Provider	Description	Source
GO:0015680	IBA	UniProt	intracellular copper ion transport	1 2 3 4 5 6 7
GO:0019430	IBA	UniProt	removal of superoxide radicals	1 2 3 4 5 6 7
GO:0006878	TAS	UniProt	cellular copper ion homeostasis	1 2 3 4 5 6 7
GO:0006801	IEA	InterPro	superoxide metabolic process
GO:0030001	IEA	InterPro	metal ion transport
GO:0055114	IEA	UniProt	oxidation-reduction process	1 2 3 4 5 6

GO term	Evidence(s)	Provider	Description	Source
GO:0008270	IBA	UniProt	zinc ion binding	1 2 3 4 5 6 7
GO:0016532	IMP, IGI	UniProt	superoxide dismutase copper chaperone activity	1 2 3 4 5 6 7 8
GO:0046872	IEA	InterPro	metal ion binding

GO term	Evidence(s)	Provider	Description	Source
GO:0005622	IBA	Gene Ontology	intracellular	1
GO:0005737	ISM	Gene Ontology	cytoplasm	1
GO:0009507	IDA, ISM	Gene Ontology	chloroplast	1 2
GO:0009570	IDA	UniProt	chloroplast stroma	1 2 3 4 5 6 7
GO:0005829	IEA	UniProt	cytosol	1 2 3 4 5 6

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR001424	Superoxide dismutase, copper/zinc binding domain
IPR006121	Heavy metal-associated domain, HMA
IPR024134	Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone

Mapman id	Description
21.6	redox.dismutases and catalases

No SignalP domains detected for this gene.