Gene: AT1G12220 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G12220
Transcript Identifier
AT1G12220.1
Gene Type
Coding gene
Location
1 : 4145011-4147680 : positive

Family

Gene family
HOM03D000020
(2209 genes in 29 species)
specific family
Subfamily
ORTHO03D000047
(245 genes in 20 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

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Descriptions

Description
Disease resistance protein (CC-NBS-LRR class) family
Curated Summary
Resistance gene, mediates resistance against the bacterial pathogen Pseudomonas syringae. Contains a putative nucleotide binding site composed of kinase-1a (or P-loop), kinase-2a, and putative kinase-3a domains, 13 imperfect leucine-rich repeats, a potential leucine zipper, and two uncharacterized motifs that are well conserved in products of previously isolated R genes. Confers resistance to Pseudomonas syringae strains that express avrPphB.
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Identifiers

Identifier Name
aliasRPS5
aliasRESISTANT TO P. SYRINGAE 5
uniprotO64973

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009626IMPUniProtplant-type hypersensitive response1 2 3 4 5 6
GO:0006952IMP, TAS, IEAGene Ontologydefense response1 2
GO:0009816IDAUniProtdefense response to bacterium, incompatible interaction1 2 3 4 5 6
GO:0008219IMPGene Ontologycell death1
GO:0006950IEAPLAZA Homologyresponse to stressHOM03D000020
GO:0050896IEAPLAZA Homologyresponse to stimulusHOM03D000020

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPIGene Ontologyprotein binding1
GO:0038023IMPUniProtsignaling receptor activity1 2 3 4 5 6
GO:0000166IMPUniProtnucleotide binding1 2 3 4 5 6
GO:0043531IEAUniProtADP binding1 2 3 4 5
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03D000020
GO:0043168IEAPLAZA Homologyanion bindingHOM03D000020
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03D000020
GO:0043167IEAPLAZA Homologyion bindingHOM03D000020
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03D000020
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03D000020
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03D000020
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03D000020
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03D000020
GO:0005488IEAPLAZA HomologybindingHOM03D000020
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03D000020
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03D000020
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03D000020
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03D000020
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03D000020
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03D000020
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03D000020

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6
GO:0005622ISSUniProtintracellular1 2 3 4 5 6
GO:0005829ISOPLAZA Tree-based OrthologycytosolAT1G61300
GO:0005739ISOPLAZA Tree-based OrthologymitochondrionAT5G47250

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000767Disease resistance protein
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR002182NB-ARC

Mapman id Description
20.1stress.biotic
No SignalP domains detected for this gene.