Gene: AT1G11310 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G11310
Transcript Identifier
AT1G11310.1
Gene Type
Coding gene
Location
1 : 3800899-3803870 : negative

Family

Gene family
HOM03D000181
(566 genes in 31 species)
specific family
Subfamily
ORTHO03D000563
(77 genes in 25 species)
specific family
Duplication type
Tandem duplicate

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Descriptions

Description
Seven transmembrane MLO family protein
Curated Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.
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Identifiers

Identifier Name
aliasPOWDERY MILDEW RESISTANT 2
aliasPMR2
aliasATMLO2
aliasMILDEW RESISTANCE LOCUS O 2
aliasMLO2
uniprotQ9SXB6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006952ISS, IEAGene Ontologydefense response1
GO:0008219ISSGene Ontologycell death1
GO:0009620IMPGene Ontologyresponse to fungus1
GO:0009817IMPUniProtdefense response to fungus, incompatible interaction1 2 3 4 5
GO:0031348IMP, RCA, UniProtnegative regulation of defense response1 2 3 4 5 6
GO:0000165RCAGene OntologyMAPK cascade1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0009595RCAGene Ontologydetection of biotic stimulus1
GO:0009617RCAGene Ontologyresponse to bacterium1
GO:0009697RCAGene Ontologysalicylic acid biosynthetic process1
GO:0009862RCAGene Ontologysystemic acquired resistance, salicylic acid mediated signaling pathway1
GO:0009867RCAGene Ontologyjasmonic acid mediated signaling pathway1
GO:0010200RCAGene Ontologyresponse to chitin1
GO:0010310RCAGene Ontologyregulation of hydrogen peroxide metabolic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0042742RCAGene Ontologydefense response to bacterium1
GO:0043900RCAGene Ontologyregulation of multi-organism process1
GO:0045087RCAGene Ontologyinnate immune response1
GO:0045088RCAGene Ontologyregulation of innate immune response1
GO:0050832RCAGene Ontologydefense response to fungus1
GO:0010150ISOPLAZA Tree-based Orthologyleaf senescenceAT2G39200
GO:0006950IEAPLAZA Homologyresponse to stressHOM03D000181
GO:0050896IEAPLAZA Homologyresponse to stimulusHOM03D000181

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005516ISSGene Ontologycalmodulin binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDA, ISSTAS, UniProtplasma membrane1 2 3 4 5 6 7
GO:0009506IDAUniProtplasmodesma1 2 3 4 5
GO:0005794IDAUniProtGolgi apparatus1 2 3 4 5
GO:0016021IEAUniProtintegral to membrane1 2 3 4
GO:0016020IEAPLAZA HomologymembraneHOM03D000181
GO:0031224IEAPLAZA Homologyintrinsic to membraneHOM03D000181
GO:0044425IEAPLAZA Homologymembrane partHOM03D000181

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004326Mlo-related protein

Mapman id Description
20.1.3.1stress.biotic.signalling.MLO-like
No SignalP domains detected for this gene.