Gene: AT1G05180 (Arabidopsis thaliana)

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Gene Identifier
AT1G05180
Transcript Identifier
AT1G05180.1
Gene Type
Coding gene
Location
1 : 1498357-1501775 : negative

Family

Gene family
HOM03D003409
(53 genes in 31 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
NAD(P)-binding Rossmann-fold superfamily protein
Curated Summary
Encodes a subunit of the RUB1 activating enzyme that regulates the protein degradation activity of Skp1-Cullin-Fbox complexes, primarily, but not exclusively, affecting auxin responses. Acts alongside AS1 to exclude BP expression from leaves.
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Identifiers

Identifier Name
aliasAXR1
aliasAUXIN RESISTANT 1
uniprotP42744

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009965IGIUniProtleaf morphogenesis1 2 3 4 5 6
GO:0010252NASUniProtauxin homeostasis1 2 3 4 5 6
GO:0016567IGI, RCA, UniProtprotein ubiquitination1 2 3 4 5 6 7
GO:0006281IMPUniProtDNA repair1 2 3 4 5 6
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0010388RCAGene Ontologycullin deneddylation1
GO:0016571RCAGene Ontologyhistone methylation1
GO:0016579RCAGene Ontologyprotein deubiquitination1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0009735IGIUniProtresponse to cytokinin1 2 3 4 5 6
GO:0009734IMPUniProtauxin mediated signaling pathway1 2 3 4 5 6
GO:0009414IMPUniProtresponse to water deprivation1 2 3 4 5 6
GO:0045116IEAUniProtprotein neddylation1 2 3 4 5
GO:0009791ISOPLAZA Tree-based Orthologypost-embryonic developmentAT2G32410

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008641IDA, ISSGene Ontologysmall protein activating enzyme activity1 2
GO:0003824IEAUniProtcatalytic activity1 2 3 4 5
GO:0005524IEAUniProtATP binding1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886ISMGene Ontologyplasma membrane1
GO:0005829IDAUniProtcytosol1 2 3 4 5 6
GO:0005634IEA, IDAUniProtnucleus1 2 3 4 5 6
GO:0005777ISOPLAZA Tree-based OrthologyperoxisomeAT2G32410

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain
IPR000594UBA/THIF-type NAD/FAD binding fold
IPR009036Molybdenum cofactor biosynthesis, MoeB

Mapman id Description
17.2.2hormone metabolism.auxin.signal transduction
No SignalP domains detected for this gene.