Gene: AT1G02500 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G02500
Transcript Identifier
AT1G02500.1
Gene Type
Coding gene
Location
1 : 519037-520218 : positive

Family

Gene family
HOM03D000844
(169 genes in 31 species)
specific family
Subfamily
ORTHO03D000210
(126 genes in 30 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
S-adenosylmethionine synthetase 1
Curated Summary
encodes a S-adenosylmethionine synthetase. SAM1 is regulated by protein S-nitrosylation. The covalent binding of nitric oxide (NO) to the Cys114 residue inhibits the enzyme activity.
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Identifiers

Identifier Name
aliasSAM1
aliasMAT1
aliasSAM-1
aliasMETK1
aliasAtSAM1
aliasS-adenosylmethionine synthetase 1
aliasS-ADENOSYLMETHIONINE SYNTHETASE-1
uniprotP23686

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006556IEA, ISSUniProtS-adenosylmethionine biosynthetic process1 2 3 4 5 6 7 8
GO:0009693TASUniProtethylene biosynthetic process1 2 3 4 5 6 7 8
GO:0046686IEP, RCA, UniProtresponse to cadmium ion1 2 3 4 5 6 7 8 9
GO:0009651IEP, RCA, UniProtresponse to salt stress1 2 3 4 5 6 7 8 9
GO:0071281IEPUniProtcellular response to iron ion1 2 3 4 5 6 7 8
GO:0006094RCAGene Ontologygluconeogenesis1
GO:0006096RCAGene Ontologyglycolysis1
GO:0006598RCAGene Ontologypolyamine catabolic process1
GO:0006833RCAGene Ontologywater transport1
GO:0006972RCAGene Ontologyhyperosmotic response1
GO:0007030RCAGene OntologyGolgi organization1
GO:0007033RCAGene Ontologyvacuole organization1
GO:0009266RCAGene Ontologyresponse to temperature stimulus1
GO:0009611RCAGene Ontologyresponse to wounding1
GO:0009698RCAGene Ontologyphenylpropanoid metabolic process1
GO:0009805RCAGene Ontologycoumarin biosynthetic process1
GO:0019344RCAGene Ontologycysteine biosynthetic process1
GO:0042398RCAGene Ontologycellular modified amino acid biosynthetic process1
GO:0006730IEAUniProtone-carbon metabolic process1 2 3 4 5 6 7
GO:0006790IEAPLAZA Homologysulfur compound metabolic processHOM03D000844
GO:0046129IEAPLAZA Homologypurine ribonucleoside biosynthetic processHOM03D000844
GO:0046128IEAPLAZA Homologypurine ribonucleoside metabolic processHOM03D000844
GO:0016053IEAPLAZA Homologyorganic acid biosynthetic processHOM03D000844
GO:0009108IEAPLAZA Homologycoenzyme biosynthetic processHOM03D000844
GO:0042455IEAPLAZA Homologyribonucleoside biosynthetic processHOM03D000844
GO:0042451IEAPLAZA Homologypurine nucleoside biosynthetic processHOM03D000844
GO:0044272IEAPLAZA Homologysulfur compound biosynthetic processHOM03D000844
GO:0008652IEAPLAZA Homologycellular amino acid biosynthetic processHOM03D000844
GO:1901657IEAPLAZA Homologyglycosyl compound metabolic processHOM03D000844
GO:1901659IEAPLAZA Homologyglycosyl compound biosynthetic processHOM03D000844
GO:0046500IEAPLAZA HomologyS-adenosylmethionine metabolic processHOM03D000844
GO:0009163IEAPLAZA Homologynucleoside biosynthetic processHOM03D000844
GO:0044283IEAPLAZA Homologysmall molecule biosynthetic processHOM03D000844
GO:0006575IEAPLAZA Homologycellular modified amino acid metabolic processHOM03D000844
GO:0051186IEAPLAZA Homologycofactor metabolic processHOM03D000844
GO:0051188IEAPLAZA Homologycofactor biosynthetic processHOM03D000844
GO:0006732IEAPLAZA Homologycoenzyme metabolic processHOM03D000844
GO:0042278IEAPLAZA Homologypurine nucleoside metabolic processHOM03D000844
GO:0006520IEAPLAZA Homologycellular amino acid metabolic processHOM03D000844
GO:1901137IEAPLAZA Homologycarbohydrate derivative biosynthetic processHOM03D000844
GO:0055086IEAPLAZA Homologynucleobase-containing small molecule metabolic processHOM03D000844
GO:0072521IEAPLAZA Homologypurine-containing compound metabolic processHOM03D000844
GO:0009116IEAPLAZA Homologynucleoside metabolic processHOM03D000844
GO:0072522IEAPLAZA Homologypurine-containing compound biosynthetic processHOM03D000844
GO:0046394IEAPLAZA Homologycarboxylic acid biosynthetic processHOM03D000844
GO:0009119IEAPLAZA Homologyribonucleoside metabolic processHOM03D000844

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004478IDA, ISSIEA, UniProtmethionine adenosyltransferase activity1 2 3 4 5 6 7 8 9
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7
GO:0016765IEAPLAZA Homologytransferase activity, transferring alkyl or aryl (other than methyl) groupsHOM03D000844

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005618IDAUniProtcell wall1 2 3 4 5 6 7 8
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7 8
GO:0016020IDAGene Ontologymembrane1
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR022630S-adenosylmethionine synthetase, C-terminal
IPR022636S-adenosylmethionine synthetase superfamily
IPR002133S-adenosylmethionine synthetase
IPR022631S-adenosylmethionine synthetase, conserved site
IPR022628S-adenosylmethionine synthetase, N-terminal
IPR022629S-adenosylmethionine synthetase, central domain

Mapman id Description
13.1.3.4.11amino acid metabolism.synthesis.aspartate family.methionine.S-adenosylmethionine synthetase
No SignalP domains detected for this gene.