Gene Overview  


General information


Gene id
AT3G50660
Species
Arabidopsis thaliana
Transcript
AT3G50660.1
Coordinates
18814262 - 18817168
Strand
negative
Chromosome
3
Type
Coding gene
Sequence
Show sequence(s)
Gene family
HOM000072   877 genes in 24 species
Sub family
ORTHO007973   22 genes in 18 species
Description
Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.;Cytochrome P450 superfamily protein
Comment
transcript
eq
 
Protein information
Cannot create amino acid sequence
 
Gene structure

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Functional annotation information


GO term(s)
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InterPro domain(s)
Interpro idDescription
IPR002401 Cytochrome P450, E-class, group I
IPR017973 Cytochrome P450, C-terminal
IPR001128 Cytochrome P450
View InterPro domain(s) mapping

Gene ids in other PLAZA versions


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