Gene Overview 
General information
- Gene id
- AT3G50660
- Species
- Arabidopsis thaliana
- Transcript
- AT3G50660.1
- Coordinates
- 18814262 - 18817168
- Strand
- negative
- Chromosome
- 3
- Type
- Coding gene
- Sequence
- Show sequence(s)
- Gene family
- HOM000072 877 genes in 24 species
- Sub family
- ORTHO007973 22 genes in 18 species
- Description
- Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.;Cytochrome P450 superfamily protein
- Comment
- transcripteqProtein informationCannot create amino acid sequence
- Gene structure
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Functional annotation information
- GO term(s)
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- InterPro domain(s)
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View InterPro domain(s) mappingInterpro id Description IPR002401 Cytochrome P450, E-class, group I IPR017973 Cytochrome P450, C-terminal IPR001128 Cytochrome P450