Gene Overview  


General information


Gene id
AT3G25070
Species
Arabidopsis thaliana
Transcript
AT3G25070.1
Coordinates
9132458 - 9133747
Strand
positive
Chromosome
3
Type
Coding gene
Sequence
Show sequence(s)
Gene family
HOM001545   76 genes in 25 species
Sub family
ORTHO005708   25 genes in 16 species
Duplication type
Tandem duplicate
Description
Encodes a member of the R protein complex and may represent a virulence target of type III pili effector proteins (virulence factors) from bacterial pathogens, which is 'guarded' by R protein complex (RPM1 and RPS2 proteins). RIN4 physically interacts with RPS2 and RPM1 in vivo. Bacterial avirulence (Avr) effectors AvrB, AvrRpm1, and AvrRpt2 induce a mobility shift in RIN4 and expression of AvrRpt2 induces rapid degradation of RIN4. RIN4 contains 2 sites for AvrRpt2 autocleavage, called RCS1 and RCS2. Overexpression of RIN4 inhibits multiple phenotypes associated with AvrRpt2 function and also inhibits PAMP-induced defense signaling. Attached to the plasma membrane at its carboxyl terminus. Cleaved by AvrRpt2 at two PxFGxW motifs, one releasing a large portion of RIN4 from the plasma membrane and both exposing amino-terminal residues that destabilized the carboxyl-terminal cleavage products by targeting them for N-end ubiquitylation and proteasomal degradation. Major virulence target of the TTSE HopF2Pto.;RPM1 interacting protein 4
Comment
transcript
eq
 
Protein information
Cannot create amino acid sequence
 
Gene structure

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Functional annotation information


GO term(s)
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Gene ids in other PLAZA versions


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