Gene Overview  


General information


Gene id
AT1G54690
Species
Arabidopsis thaliana
Transcript
AT1G54690.1
Coordinates
20414607 - 20415206
Strand
negative
Chromosome
1
Type
Coding gene
Sequence
Show sequence(s)
Gene family
HOM000175   418 genes in 25 species
Sub family
ORTHO010951   18 genes in 16 species
Duplication type
Block duplicate
Description
Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10–20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.;gamma histone variant H2AX
Comment
transcript
eq
 
Protein information
Cannot create amino acid sequence
 
Gene structure

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Functional annotation information


GO term(s)
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InterPro domain(s)
Interpro idDescription
IPR002119 Histone H2A
IPR009072 Histone-fold
IPR007125 Histone core
View InterPro domain(s) mapping

Gene ids in other PLAZA versions


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