Gene: YLR143W (Saccharomyces cerevisiae strain S288C)

Overview top

Gene Identifier
YLR143W
Transcript Identifier
YLR143W
Gene Type
Coding gene
Location
XII : 427329-429386 : positive

Family Information

Homologous gene family
HOM03P001960
(42 genes in 39 species)
specific family

Descriptions

gene_descr
Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene

Identifiers

Type Value
UniprotQ12429
pidYLR143W
SGDS000004133

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No GO associations found for this gene.
InterPro Description
IPR002761Diphthamide synthase domain
IPR006175YjgF/YER057c/UK114 family
IPR013813Endoribonuclease L-PSP/chorismate mutase-like
IPR014729Rossmann-like alpha/beta/alpha sandwich fold
IPR030662Diphthine--ammonia ligase/Uncharacterised protein MJ0570

No MapMan annotations defined for this gene.