Gene: FBgn0023172 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0023172
Transcript Identifier
FBtr0086971
Gene Type
Coding gene
Location
2R : 17028996-17044320 : positive

Family Information

Homologous gene family
HOM03P004874
(19 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P029124
(4 genes in 4 species)
specific family

Descriptions

gene_descr
Rho guanine nucleotide exchange factor 2

Identifiers

Type Value
pidFBpp0086125
UniprotA1ZAN6
UniprotE8NH10
UniprotO44113
UniprotO44381
UniprotQ8T9E3

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
IMP
Genome Projectactin filament organization
GO:0007277
IMP
Genome Projectpole cell development
GO:0007349
IMP
Genome Projectcellularization
GO:0007369
TAS
Genome Projectgastrulation
GO:0007370
IMP
Genome Projectventral furrow formation
GO:0007374
IMP
Genome Projectposterior midgut invagination
GO:0007375
IMP
Genome Projectanterior midgut invagination
GO:0007377
IMP
Genome Projectgerm-band extension
GO:0008360
IMP
Genome Projectregulation of cell shape
GO:0016331
IMP
Genome Projectmorphogenesis of embryonic epithelium
GO:0016476
IMP, IGI
NAS
Genome Projectregulation of embryonic cell shape
GO:0030589
IMP
Genome Projectpseudocleavage involved in syncytial blastoderm formation
GO:0031532
IMP
Genome Projectactin cytoskeleton reorganization
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035025
IMP
Genome Projectpositive regulation of Rho protein signal transduction
GO:0035277
IMP
Genome Projectspiracle morphogenesis, open tracheal system
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0038032
IEA
Genome Projecttermination of G-protein coupled receptor signaling pathway
GO:0043547
IMP
ISS
TAS, IEA
Genome Projectpositive regulation of GTPase activity
GO:0050770
IGI
Genome Projectregulation of axonogenesis
GO:0070252
IGI
Genome Projectactin-mediated cell contraction
GO:0090254
IMP
Genome Projectcell elongation involved in imaginal disc-derived wing morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005089
IMP
ISS
TAS, IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005826
IDA
Genome Projectactomyosin contractile ring
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0016328
IDA
Genome Projectlateral plasma membrane
GO:0030478
IDA
Genome Projectactin cap
GO:0045177
IDA
Genome Projectapical part of cell
GO:0045178
IDA
Genome Projectbasal part of cell
GO:0045179
IDA
Genome Projectapical cortex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000219Dbl homology (DH) domain
IPR001478PDZ domain
IPR001849Pleckstrin homology domain
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR011993PH domain-like
IPR015212Regulator of G protein signalling-like domain
IPR016137RGS domain

No MapMan annotations defined for this gene.