Gene: FBgn0004644 (Drosophila melanogaster)

Overview top

Gene Identifier
FBgn0004644
Transcript Identifier
FBtr0100506
Gene Type
Coding gene
Location
3R : 23128738-23141521 : negative

Family Information

Homologous gene family
HOM03P007513
(11 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P028121
(4 genes in 4 species)
specific family

Descriptions

gene_descr
hedgehog

Identifiers

Type Value
pidFBpp0099945
UniprotQ02936

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001745
TAS
Genome Projectcompound eye morphogenesis
GO:0001746
IMP
Genome ProjectBolwig's organ morphogenesis
GO:0001751
TAS
Genome Projectcompound eye photoreceptor cell differentiation
GO:0002385
IMP
Genome Projectmucosal immune response
GO:0006357
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006508
IEA
Genome Projectproteolysis
GO:0007154
IEA
Genome Projectcell communication
GO:0007224
IGI
TAS, NAS
Genome Projectsmoothened signaling pathway
GO:0007228
IGI
Genome Projectpositive regulation of hh target transcription factor activity
GO:0007267
IEA
Genome Projectcell-cell signaling
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007280
IGI
Genome Projectpole cell migration
GO:0007346
IMP
Genome Projectregulation of mitotic cell cycle
GO:0007367
IMP, IEP
TAS, NAS, IEA
Genome Projectsegment polarity determination
GO:0007386
TAS
Genome Projectcompartment pattern specification
GO:0007398
NAS
Genome Projectectoderm development
GO:0007418
IMP
Genome Projectventral midline development
GO:0007424
TAS
Genome Projectopen tracheal system development
GO:0007427
IMP
Genome Projectepithelial cell migration, open tracheal system
GO:0007440
TAS
Genome Projectforegut morphogenesis
GO:0007442
IMP
TAS
Genome Projecthindgut morphogenesis
GO:0007446
TAS
Genome Projectimaginal disc growth
GO:0007447
NAS
Genome Projectimaginal disc pattern formation
GO:0007458
IMP, IGI, IEP
TAS
Genome Projectprogression of morphogenetic furrow involved in compound eye morphogenesis
GO:0007473
TAS
Genome Projectwing disc proximal/distal pattern formation
GO:0007474
TAS
Genome Projectimaginal disc-derived wing vein specification
GO:0007478
TAS
Genome Projectleg disc morphogenesis
GO:0007487
TAS
Genome Projectanalia development
GO:0007498
NAS
Genome Projectmesoderm development
GO:0007506
IMP
Genome Projectgonadal mesoderm development
GO:0007507
TAS, NAS
Genome Projectheart development
GO:0008347
IMP
Genome Projectglial cell migration
GO:0008354
IMP
Genome Projectgerm cell migration
GO:0008544
TAS
Genome Projectepidermis development
GO:0008595
NAS
Genome Projectanterior/posterior axis specification, embryo
GO:0009653
IEA
Genome Projectanatomical structure morphogenesis
GO:0009880
IEP
Genome Projectembryonic pattern specification
GO:0016335
IMP
Genome Projectmorphogenesis of larval imaginal disc epithelium
GO:0016539
IEA
Genome Projectintein-mediated protein splicing
GO:0016540
IDA, IMP
Genome Projectprotein autoprocessing
GO:0021960
IMP
Genome Projectanterior commissure morphogenesis
GO:0030707
TAS
Genome Projectovarian follicle cell development
GO:0030713
TAS
Genome Projectovarian follicle cell stalk formation
GO:0031397
IDA
Genome Projectnegative regulation of protein ubiquitination
GO:0035215
IMP
TAS
Genome Projectgenital disc development
GO:0035217
IMP
Genome Projectlabial disc development
GO:0035224
IEP
Genome Projectgenital disc anterior/posterior pattern formation
GO:0035231
IMP
Genome Projectcytoneme assembly
GO:0035232
TAS
Genome Projectgerm cell attraction
GO:0035277
IMP
Genome Projectspiracle morphogenesis, open tracheal system
GO:0035288
TAS
Genome Projectanterior head segmentation
GO:0035289
TAS
Genome Projectposterior head segmentation
GO:0035290
TAS
Genome Projecttrunk segmentation
GO:0040007
NAS
Genome Projectgrowth
GO:0042078
TAS
Genome Projectgerm-line stem cell division
GO:0042127
NAS
Genome Projectregulation of cell proliferation
GO:0042306
IMP
Genome Projectregulation of protein import into nucleus
GO:0042993
IMP
Genome Projectpositive regulation of transcription factor import into nucleus
GO:0045168
IMP
Genome Projectcell-cell signaling involved in cell fate commitment
GO:0045464
NAS
Genome ProjectR8 cell fate specification
GO:0045743
IMP
Genome Projectpositive regulation of fibroblast growth factor receptor signaling pathway
GO:0045861
IMP
Genome Projectnegative regulation of proteolysis
GO:0045880
TAS
Genome Projectpositive regulation of smoothened signaling pathway
GO:0046620
TAS
Genome Projectregulation of organ growth
GO:0048066
TAS
Genome Projectdevelopmental pigmentation
GO:0048099
TAS
Genome Projectanterior/posterior lineage restriction, imaginal disc
GO:0048100
TAS
Genome Projectwing disc anterior/posterior pattern formation
GO:0048103
TAS
Genome Projectsomatic stem cell division
GO:0048592
IMP
Genome Projecteye morphogenesis
GO:0060914
IMP
Genome Projectheart formation
GO:2000274
IMP
Genome Projectregulation of epithelial cell migration, open tracheal system

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005113
TAS, NAS
Genome Projectpatched binding
GO:0005119
NAS
Genome Projectsmoothened binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0016015
TAS, IEA
Genome Projectmorphogen activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, NAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005768
IDA
Genome Projectendosome
GO:0005886
IDA
NAS, IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030139
IDA
Genome Projectendocytic vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000320Hedgehog, N-terminal signalling domain
IPR001657Hedgehog protein
IPR001767Hedgehog protein, Hint domain
IPR003586Hint domain C-terminal
IPR003587Hint domain N-terminal
IPR006141Intein N-terminal splicing region
IPR009045Hedgehog signalling/DD-peptidase zinc-binding domain
IPR028992Hedgehog/Intein (Hint) domain

No MapMan annotations defined for this gene.