Gene: ENSMUSG00000079487 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000079487
Transcript Identifier
ENSMUST00000087948
Gene Type
Coding gene
Location
X : 101274261-101297230 : positive

Family Information

Homologous gene family
HOM03P011387
(7 genes in 5 species)
specific family

Descriptions

gene_descr
mediator complex subunit 12

Identifiers

Type Value
UniprotA2AGH6
MGI1926212

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001843
IMP
Genome Projectneural tube closure
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006367
ISO
IEA
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0007507
IMP
Genome Projectheart development
GO:0014003
IMP
Genome Projectoligodendrocyte development
GO:0014044
IMP
Genome ProjectSchwann cell development
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0019827
IMP
Genome Projectstem cell population maintenance
GO:0030178
ISO
IEA
Genome Projectnegative regulation of Wnt signaling pathway
GO:0030518
ISO
IEA
Genome Projectintracellular steroid hormone receptor signaling pathway
GO:0030521
ISO
IEA
Genome Projectandrogen receptor signaling pathway
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0060070
IMP
Genome Projectcanonical Wnt signaling pathway
GO:0060071
IMP
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0090245
IMP
Genome Projectaxis elongation involved in somitogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001104
ISO, IBA
IEA
Genome ProjectRNA polymerase II transcription cofactor activity
GO:0001105
IBA
Genome ProjectRNA polymerase II transcription coactivator activity
GO:0001190
IGI
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003712
ISO
IEA
Genome Projecttranscription cofactor activity
GO:0003713
ISO
IEA
Genome Projecttranscription coactivator activity
GO:0004872
ISO
IEA
Genome Projectreceptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
IEA
Genome Projectbeta-catenin binding
GO:0008022
ISO
IEA
Genome Projectprotein C-terminus binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0019904
ISO
IEA
Genome Projectprotein domain specific binding
GO:0046966
ISO
IEA
Genome Projectthyroid hormone receptor binding
GO:0061630
IEA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000151
IEA
Genome Projectubiquitin ligase complex
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
TAS, IEA
Genome Projectnucleoplasm
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0005813
ISO
IEA
Genome Projectcentrosome
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016592
IDA
ISO
IEA
Genome Projectmediator complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR019035Mediator complex, subunit Med12
IPR021989Mediator complex, subunit Med12, catenin-binding
IPR021990Mediator complex, subunit Med12, LCEWAV-domain

No MapMan annotations defined for this gene.