Gene: ENSMUSG00000076431 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000076431
Transcript Identifier
ENSMUST00000067230
Gene Type
Coding gene
Location
13 : 28951699-28953021 : negative

Family Information

Homologous gene family
HOM03P001338
(53 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P062712
(2 genes in 2 species)
specific family

Descriptions

gene_descr
SRY (sex determining region Y)-box 4

Identifiers

Type Value
UniprotQ06831
MGI98366

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001501
IMP
Genome Projectskeletal system development
GO:0001841
IMP
Genome Projectneural tube formation
GO:0002328
IMP
Genome Projectpro-B cell differentiation
GO:0003183
IMP
Genome Projectmitral valve morphogenesis
GO:0003211
IMP
Genome Projectcardiac ventricle formation
GO:0003215
IMP
Genome Projectcardiac right ventricle morphogenesis
GO:0003289
IMP
Genome Projectatrial septum primum morphogenesis
GO:0003357
IMP
Genome Projectnoradrenergic neuron differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
ISS, ISO
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
ISO
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006977
ISS, ISO
IEA
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007507
IMP
Genome Projectheart development
GO:0008284
IMP
ISS, ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
ISS, ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0014009
IMP
Genome Projectglial cell proliferation
GO:0021510
IMP
Genome Projectspinal cord development
GO:0021522
IMP
Genome Projectspinal cord motor neuron differentiation
GO:0021782
IMP
Genome Projectglial cell development
GO:0030177
IMP
Genome Projectpositive regulation of Wnt signaling pathway
GO:0030217
IMP
Genome ProjectT cell differentiation
GO:0031018
IMP
Genome Projectendocrine pancreas development
GO:0031397
ISS, ISO
IEA
Genome Projectnegative regulation of protein ubiquitination
GO:0031647
ISS, ISO
IEA
Genome Projectregulation of protein stability
GO:0032024
IMP
Genome Projectpositive regulation of insulin secretion
GO:0035019
IDA
Genome Projectsomatic stem cell population maintenance
GO:0035910
IMP
Genome Projectascending aorta morphogenesis
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0042769
ISS, ISO
IEA
Genome ProjectDNA damage response, detection of DNA damage
GO:0043065
ISO
IEA
Genome Projectpositive regulation of apoptotic process
GO:0045727
ISS, ISO
IEA
Genome Projectpositive regulation of translation
GO:0045893
IDA
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
ISS, ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046826
ISS, ISO
IEA
Genome Projectnegative regulation of protein export from nucleus
GO:0048485
IMP
Genome Projectsympathetic nervous system development
GO:0050821
IMP
ISO
IEA
Genome Projectprotein stabilization
GO:0060070
IMP
Genome Projectcanonical Wnt signaling pathway
GO:0060174
IMP
Genome Projectlimb bud formation
GO:0060412
IMP
Genome Projectventricular septum morphogenesis
GO:0060548
IMP
Genome Projectnegative regulation of cell death
GO:0060563
IMP
Genome Projectneuroepithelial cell differentiation
GO:0060993
IMP
Genome Projectkidney morphogenesis
GO:0071333
IMP
Genome Projectcellular response to glucose stimulus
GO:0090263
IDA
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:2000761
ISS, ISO
IEA
Genome Projectpositive regulation of N-terminal peptidyl-lysine acetylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000976
IDA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000981
IDA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046
IDA
ISO
IEA
Genome Projectcore promoter sequence-specific DNA binding
GO:0001071
ISS
IEA
Genome Projectnucleic acid binding transcription factor activity
GO:0001077
IDA
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001105
IDA
Genome ProjectRNA polymerase II transcription coactivator activity
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IDA
ISS, ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0046982
IDA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0005739
ISS, ISO
IEA
Genome Projectmitochondrion
GO:0044798
IDA
Genome Projectnuclear transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009071High mobility group box domain

No MapMan annotations defined for this gene.