Gene: ENSMUSG00000074582 (Mus musculus)

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Gene Identifier
ENSMUSG00000074582
Transcript Identifier
ENSMUST00000099078
Gene Type
Coding gene
Location
2 : 166805715-166894788 : positive

Family Information

Homologous gene family
HOM03P000148
(206 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000156
(69 genes in 39 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

Identifiers

Type Value
UniprotA2A5R2
MGI2139354

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001881
ISS, ISO
IEA
Genome Projectreceptor recycling
GO:0006810
IEA
Genome Projecttransport
GO:0006887
IEA
Genome Projectexocytosis
GO:0006893
ISS, ISO
IEA
Genome ProjectGolgi to plasma membrane transport
GO:0007032
ISS, ISO
IEA
Genome Projectendosome organization
GO:0010256
ISS, ISO
IEA
Genome Projectendomembrane system organization
GO:0015031
IEA
Genome Projectprotein transport
GO:0016192
IBA
Genome Projectvesicle-mediated transport
GO:0032012
IEA
Genome Projectregulation of ARF protein signal transduction
GO:0032760
ISS, ISO
IEA
Genome Projectpositive regulation of tumor necrosis factor production
GO:0035556
ISO
IEA
Genome Projectintracellular signal transduction
GO:0043547
ISO
Genome Projectpositive regulation of GTPase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
ISO
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005086
ISS, ISO, IBA
IEA
Genome ProjectARF guanyl-nucleotide exchange factor activity
GO:0017022
IEA
Genome Projectmyosin binding
GO:0034237
ISS, ISO
IEA
Genome Projectprotein kinase A regulatory subunit binding
GO:0050811
ISS
IEA
Genome ProjectGABA receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
ISS, ISO
IEA
Genome ProjectGolgi membrane
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005802
ISS, IBA
IEA
Genome Projecttrans-Golgi network
GO:0005815
ISS, ISO
IEA
Genome Projectmicrotubule organizing center
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005879
ISS
IEA
Genome Projectaxonemal microtubule
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016023
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0031410
ISS
IEA
Genome Projectcytoplasmic vesicle
GO:0032279
ISS
IEA
Genome Projectasymmetric synapse
GO:0032280
ISS
IEA
Genome Projectsymmetric synapse
GO:0042995
IEA
Genome Projectcell projection
GO:0043197
ISS
IEA
Genome Projectdendritic spine
GO:0045202
IEA
Genome Projectsynapse
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0055037
ISS, ISO
IEA
Genome Projectrecycling endosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000904Sec7 domain
IPR011989Armadillo-like helical
IPR015403Sec7, C-terminal
IPR016024Armadillo-type fold
IPR023394Sec7 domain, alpha orthogonal bundle
IPR032629Mon2, dimerisation and cyclophilin-binding domain

No MapMan annotations defined for this gene.