Gene: ENSMUSG00000067212 (Mus musculus)

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Gene Identifier
ENSMUSG00000067212
Transcript Identifier
ENSMUST00000102678
Gene Type
Coding gene
Location
17 : 36030188-36032669 : negative

Family Information

Homologous gene family
HOM03P000618
(85 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P000429
(50 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
histocompatibility 2, T region locus 23

Identifiers

Type Value
UniprotP06339
UniprotQ3V014
MGI95957

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IDA
ISO
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002250
ISO
Genome Projectadaptive immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002474
IBA
IEA
Genome Projectantigen processing and presentation of peptide antigen via MHC class I
GO:0002476
ISO
Genome Projectantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002489
IDA
Genome Projectantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002715
ISO
Genome Projectregulation of natural killer cell mediated immunity
GO:0002717
ISO
Genome Projectpositive regulation of natural killer cell mediated immunity
GO:0006955
IEA
Genome Projectimmune response
GO:0019731
ISO
Genome Projectantibacterial humoral response
GO:0019882
IEA
Genome Projectantigen processing and presentation
GO:0032736
ISO
Genome Projectpositive regulation of interleukin-13 production
GO:0032753
ISO
Genome Projectpositive regulation of interleukin-4 production
GO:0032759
ISO
Genome Projectpositive regulation of TRAIL production
GO:0032760
ISO
Genome Projectpositive regulation of tumor necrosis factor production
GO:0036037
ISO
Genome ProjectCD8-positive, alpha-beta T cell activation
GO:0042270
ISO
Genome Projectprotection from natural killer cell mediated cytotoxicity
GO:0048839
IDA
Genome Projectinner ear development
GO:0050830
ISO
Genome Projectdefense response to Gram-positive bacterium
GO:0051024
ISO
Genome Projectpositive regulation of immunoglobulin secretion
GO:2000566
ISO
Genome Projectpositive regulation of CD8-positive, alpha-beta T cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
ISO, IBA
Genome Projectreceptor binding
GO:0030881
ISO
Genome Projectbeta-2-microglobulin binding
GO:0042288
ISO
Genome ProjectMHC class I protein binding
GO:0042605
ISO, IBA
IEA
Genome Projectpeptide antigen binding
GO:0046703
ISO
Genome Projectnatural killer cell lectin-like receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IBA
Genome Projectplasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030670
TAS
Genome Projectphagocytic vesicle membrane
GO:0032398
ISO
Genome ProjectMHC class Ib protein complex
GO:0042612
ISO
IEA
Genome ProjectMHC class I protein complex
GO:0070062
ISO
Genome Projectextracellular exosome
GO:0071556
TAS
Genome Projectintegral component of lumenal side of endoplasmic reticulum membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001039MHC class I alpha chain, alpha1 alpha2 domains
IPR003006Immunoglobulin/major histocompatibility complex, conserved site
IPR003597Immunoglobulin C1-set
IPR007110Immunoglobulin-like domain
IPR011161MHC class I-like antigen recognition-like
IPR011162MHC classes I/II-like antigen recognition protein
IPR013783Immunoglobulin-like fold
IPR027648MHC class I alpha chain

No MapMan annotations defined for this gene.