Gene: ENSMUSG00000064177 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000064177
Transcript Identifier
ENSMUST00000064993
Gene Type
Coding gene
Location
6 : 113716250-113719429 : negative

Family Information

Homologous gene family
HOM03P049934
(2 genes in 2 species)
specific family

Descriptions

gene_descr
ghrelin

Identifiers

Type Value
UniprotQ9EQX0
UniprotA2RSS9
MGI1930008

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISS, ISO
IEA
Genome Projectactivation of MAPK activity
GO:0001696
IBA
IEA
Genome Projectgastric acid secretion
GO:0001937
ISS, ISO
IEA
Genome Projectnegative regulation of endothelial cell proliferation
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
ISS
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0008154
ISS, ISO
IEA
Genome Projectactin polymerization or depolymerization
GO:0008542
ISO
Genome Projectvisual learning
GO:0009725
ISS, ISO
IEA
Genome Projectresponse to hormone
GO:0009755
IBA
Genome Projecthormone-mediated signaling pathway
GO:0016358
IMP
ISS, ISO
IEA
Genome Projectdendrite development
GO:0032024
ISS
IEA
Genome Projectpositive regulation of insulin secretion
GO:0032095
ISS
IEA
Genome Projectregulation of response to food
GO:0032097
ISS
IEA
Genome Projectpositive regulation of response to food
GO:0032100
IDA, IMP, IGI
Genome Projectpositive regulation of appetite
GO:0032691
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-1 beta production
GO:0040013
IMP
Genome Projectnegative regulation of locomotion
GO:0042127
ISS, ISO
IEA
Genome Projectregulation of cell proliferation
GO:0042322
ISO
IEA
Genome Projectnegative regulation of circadian sleep/wake cycle, REM sleep
GO:0042536
ISS, ISO
IEA
Genome Projectnegative regulation of tumor necrosis factor biosynthetic process
GO:0043066
ISS, ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043627
ISS, ISO
IEA
Genome Projectresponse to estrogen
GO:0045409
ISS, ISO
IEA
Genome Projectnegative regulation of interleukin-6 biosynthetic process
GO:0046010
ISO
IEA
Genome Projectpositive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046676
IMP
ISS, ISA
IEA
Genome Projectnegative regulation of insulin secretion
GO:0046697
ISS, ISO
IEA
Genome Projectdecidualization
GO:0050728
ISS, ISO, IBA
IEA
Genome Projectnegative regulation of inflammatory response
GO:0051461
ISO
IEA
Genome Projectpositive regulation of corticotropin secretion
GO:0051464
ISO
IEA
Genome Projectpositive regulation of cortisol secretion
GO:0051965
IMP
ISS, ISO
IEA
Genome Projectpositive regulation of synapse assembly
GO:0060079
IMP
Genome Projectexcitatory postsynaptic potential
GO:0060124
ISO, IBA
IEA
Genome Projectpositive regulation of growth hormone secretion
GO:0061098
ISO, IBA
IEA
Genome Projectpositive regulation of protein tyrosine kinase activity
GO:2000506
IDA
Genome Projectnegative regulation of energy homeostasis
GO:2000507
IDA
Genome Projectpositive regulation of energy homeostasis
GO:0008343
IDA
Genome Projectadult feeding behavior

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001664
IEA
Genome ProjectG-protein coupled receptor binding
GO:0005179
ISS
TAS, IEA
Genome Projecthormone activity
GO:0016608
ISS, IBA
IEA
Genome Projectgrowth hormone-releasing hormone activity
GO:0030296
ISS, ISO
IEA
Genome Projectprotein tyrosine kinase activator activity
GO:0031768
ISS, IBA
IEA
Genome Projectghrelin receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
ISS, ISO
IEA
Genome Projectextracellular region
GO:0005615
ISS, ISO, IBA
IEA
Genome Projectextracellular space
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005829
ISS
IEA
Genome Projectcytosol
GO:0030424
ISS, ISO
IEA
Genome Projectaxon

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005441Preproghrelin peptide
IPR006737Motilin/ghrelin-associated peptide
IPR006738Motilin/ghrelin

No MapMan annotations defined for this gene.