Gene: ENSMUSG00000062960 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000062960
Transcript Identifier
ENSMUST00000113516
Gene Type
Coding gene
Location
5 : 75934423-75978168 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P018477
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
kinase insert domain protein receptor

Identifiers

Type Value
UniprotQ8VCD0
MGI96683

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001541
IMP
Genome Projectovarian follicle development
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0001934
ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0001938
ISO
IEA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0001945
IGI
Genome Projectlymph vessel development
GO:0002053
IMP
Genome Projectpositive regulation of mesenchymal cell proliferation
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007169
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008360
ISO
IEA
Genome Projectregulation of cell shape
GO:0010595
ISO
IEA
Genome Projectpositive regulation of endothelial cell migration
GO:0014068
ISO
IEA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IGI
Genome Projectcell migration
GO:0018108
ISO
IEA
Genome Projectpeptidyl-tyrosine phosphorylation
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030324
IMP
Genome Projectlung development
GO:0030335
ISO
IEA
Genome Projectpositive regulation of cell migration
GO:0035584
ISO
IEA
Genome Projectcalcium-mediated signaling using intracellular calcium source
GO:0035924
ISO
IEA
Genome Projectcellular response to vascular endothelial growth factor stimulus
GO:0038084
ISO
Genome Projectvascular endothelial growth factor signaling pathway
GO:0043066
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043129
IMP
Genome Projectsurfactant homeostasis
GO:0043410
ISO
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0045165
IMP
Genome Projectcell fate commitment
GO:0045446
IDA
Genome Projectendothelial cell differentiation
GO:0045601
IMP
Genome Projectregulation of endothelial cell differentiation
GO:0045766
ISO
IEA
Genome Projectpositive regulation of angiogenesis
GO:0046777
ISO
IEA
Genome Projectprotein autophosphorylation
GO:0048010
IDA
ISO
IEA
Genome Projectvascular endothelial growth factor receptor signaling pathway
GO:0048286
IMP
Genome Projectlung alveolus development
GO:0048469
IMP
Genome Projectcell maturation
GO:0048754
IMP
Genome Projectbranching morphogenesis of an epithelial tube
GO:0050679
IMP
Genome Projectpositive regulation of epithelial cell proliferation
GO:0050927
ISO
IEA
Genome Projectpositive regulation of positive chemotaxis
GO:0051770
ISO
IEA
Genome Projectpositive regulation of nitric-oxide synthase biosynthetic process
GO:0051894
ISO
IEA
Genome Projectpositive regulation of focal adhesion assembly
GO:0055074
IDA
Genome Projectcalcium ion homeostasis
GO:0070374
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:1901532
IMP
Genome Projectregulation of hematopoietic progenitor cell differentiation
GO:2000352
ISO
IEA
Genome Projectnegative regulation of endothelial cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
ISO
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005021
IDA
ISO
IEA
Genome Projectvascular endothelial growth factor-activated receptor activity
GO:0005178
ISO
IEA
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019838
IPI
ISO
IEA
Genome Projectgrowth factor binding
GO:0038085
ISO
IEA
Genome Projectvascular endothelial growth factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005768
ISO
IEA
Genome Projectendosome
GO:0005783
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005794
ISO
IEA
Genome ProjectGolgi apparatus
GO:0005886
ISO
Genome Projectplasma membrane
GO:0005887
ISO
IEA
Genome Projectintegral component of plasma membrane
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0045121
ISO
IEA
Genome Projectmembrane raft
GO:0071944
IDA
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001824Tyrosine-protein kinase, receptor class III, conserved site
IPR003598Immunoglobulin subtype 2
IPR003599Immunoglobulin subtype
IPR007110Immunoglobulin-like domain
IPR008266Tyrosine-protein kinase, active site
IPR009136Vascular endothelial growth factor receptor 2 (VEGFR2)
IPR011009Protein kinase-like domain
IPR013098Immunoglobulin I-set
IPR013151Immunoglobulin
IPR013783Immunoglobulin-like fold
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.