Gene: ENSMUSG00000060063 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000060063
Transcript Identifier
ENSMUST00000071130
Gene Type
Coding gene
Location
5 : 149265113-149287734 : positive

Family Information

Homologous gene family
HOM03P017115
(5 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P076328
(2 genes in 2 species)
specific family

Descriptions

gene_descr
arachidonate 5-lipoxygenase activating protein

Identifiers

Type Value
UniprotP30355
MGI107505

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002540
IMP
Genome Projectleukotriene production involved in inflammatory response
GO:0002675
IEA
Genome Projectpositive regulation of acute inflammatory response
GO:0006691
IEA
Genome Projectleukotriene metabolic process
GO:0019370
IDA, IMP
ISO
IEA
Genome Projectleukotriene biosynthetic process
GO:0043085
IEA
Genome Projectpositive regulation of catalytic activity
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070207
ISO
IEA
Genome Projectprotein homotrimerization
GO:0071277
ISO
Genome Projectcellular response to calcium ion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004051
IEA
Genome Projectarachidonate 5-lipoxygenase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008047
IEA
Genome Projectenzyme activator activity
GO:0019899
IEA
Genome Projectenzyme binding
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0046982
IEA
Genome Projectprotein heterodimerization activity
GO:0047485
ISO
Genome Projectprotein N-terminus binding
GO:0050544
ISS, ISO
Genome Projectarachidonic acid binding
GO:0004364
IBA
Genome Projectglutathione transferase activity
GO:0004464
IBA
Genome Projectleukotriene-C4 synthase activity
GO:0004602
IBA
Genome Projectglutathione peroxidase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005635
ISS, ISO, IBA
Genome Projectnuclear envelope
GO:0005783
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
IEA
Genome Projectcytosol
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031965
ISS, ISO
IEA
Genome Projectnuclear membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001129Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
IPR0014465-lipoxygenase-activating protein
IPR018295FLAP/GST2/LTC4S, conserved site
IPR023352Membrane associated eicosanoid/glutathione metabolism-like domain

No MapMan annotations defined for this gene.