Gene: ENSMUSG00000059923 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000059923
Transcript Identifier
ENSMUST00000021090
Gene Type
Coding gene
Location
11 : 115645769-115699229 : negative

Family Information

Homologous gene family
HOM03P006490
(13 genes in 4 species)
specific family

Descriptions

gene_descr
growth factor receptor bound protein 2

Identifiers

Type Value
UniprotQ60631
UniprotQ3U5I5
MGI95805

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007265
TAS, IEA
Genome ProjectRas protein signal transduction
GO:0007568
IEA
Genome Projectaging
GO:0008286
ISO
IEA
Genome Projectinsulin receptor signaling pathway
GO:0009967
IDA
IEA
Genome Projectpositive regulation of signal transduction
GO:0030154
IMP
Genome Projectcell differentiation
GO:0030838
IGI
Genome Projectpositive regulation of actin filament polymerization
GO:0031623
ISO
IEA
Genome Projectreceptor internalization
GO:0042770
ISO
IEA
Genome Projectsignal transduction in response to DNA damage
GO:0043408
IGI
Genome Projectregulation of MAPK cascade
GO:0048646
IMP
Genome Projectanatomical structure formation involved in morphogenesis
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0060670
IMP
Genome Projectbranching involved in labyrinthine layer morphogenesis
GO:0071479
ISO
IEA
Genome Projectcellular response to ionizing radiation
GO:2000379
ISO
IEA
Genome Projectpositive regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001784
IEA
Genome Projectphosphotyrosine binding
GO:0005070
IDA
IEA
Genome ProjectSH3/SH2 adaptor activity
GO:0005154
ISO
IEA
Genome Projectepidermal growth factor receptor binding
GO:0005168
ISO
IEA
Genome Projectneurotrophin TRKA receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017124
ISS, ISO
IEA
Genome ProjectSH3 domain binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0019904
IPI
IEA
Genome Projectprotein domain specific binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0043560
ISO
IEA
Genome Projectinsulin receptor substrate binding
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding
GO:0046875
IPI
ISO
IEA
Genome Projectephrin receptor binding
GO:0051219
IEA
Genome Projectphosphoprotein binding
GO:0019903
IPI
Genome Projectprotein phosphatase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005768
ISS, ISO
IEA
Genome Projectendosome
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0008180
IDA
ISO
IEA
Genome ProjectCOP9 signalosome
GO:0012506
IDA
Genome Projectvesicle membrane
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0043234
IEA
Genome Projectprotein complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0070436
ISO
IEA
Genome ProjectGrb2-EGFR complex
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000980SH2 domain
IPR001452SH3 domain

No MapMan annotations defined for this gene.