Gene: ENSMUSG00000058488 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000058488
Transcript Identifier
ENSMUST00000078856
Gene Type
Coding gene
Location
5 : 150952717-150991854 : positive

Family Information

Homologous gene family
HOM03P000144
(208 genes in 27 species)
specific family
Orthologous gene family
ORTHO03P000792
(43 genes in 22 species)
specific family

Descriptions

gene_descr
klotho

Identifiers

Type Value
UniprotO35082
MGI1101771

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002526
IEA
Genome Projectacute inflammatory response
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0006112
IMP
Genome Projectenergy reserve metabolic process
GO:0007568
IMP
ISO
IEA
Genome Projectaging
GO:0008152
IEA
Genome Projectmetabolic process
GO:0008286
IEA
Genome Projectinsulin receptor signaling pathway
GO:0008543
IEA
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0030501
ISO
IEA
Genome Projectpositive regulation of bone mineralization
GO:0055074
IGI
Genome Projectcalcium ion homeostasis
GO:0090080
IGI
Genome Projectpositive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004553
IEA
Genome Projecthydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566
IEA
Genome Projectbeta-glucuronidase activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0005104
IPI
Genome Projectfibroblast growth factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016798
IEA
Genome Projecthydrolase activity, acting on glycosyl bonds
GO:0017134
IPI
ISO
IEA
Genome Projectfibroblast growth factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
ISS
IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
ISS
IEA
Genome Projectintegral component of membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001360Glycoside hydrolase, family 1
IPR013781Glycoside hydrolase, catalytic domain
IPR017853Glycoside hydrolase superfamily
IPR018120Glycoside hydrolase, family 1, active site
IPR028546Klotho

No MapMan annotations defined for this gene.