Gene: ENSMUSG00000058230 (Mus musculus)

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Gene Identifier
ENSMUSG00000058230
Transcript Identifier
ENSMUST00000171937
Gene Type
Coding gene
Location
7 : 16497653-16565138 : negative

Family Information

Homologous gene family
HOM03P000257
(144 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P015165
(6 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
Rho GTPase activating protein 35

Identifiers

Type Value
UniprotQ91YM2
UniprotB2RTN5
MGI1929494

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001843
IMP
Genome Projectneural tube closure
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007229
TAS
Genome Projectintegrin-mediated signaling pathway
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0008360
IDA
Genome Projectregulation of cell shape
GO:0010976
IGI
Genome Projectpositive regulation of neuron projection development
GO:0030900
IMP
Genome Projectforebrain development
GO:0035024
IDA, IGI
Genome Projectnegative regulation of Rho protein signal transduction
GO:0043010
IMP
Genome Projectcamera-type eye development
GO:0043116
IMP
Genome Projectnegative regulation of vascular permeability
GO:0043547
TAS, IEA
Genome Projectpositive regulation of GTPase activity
GO:0045892
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
ISO
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0005096
TAS, IEA
Genome ProjectGTPase activator activity
GO:0005525
IEA
Genome ProjectGTP binding
GO:0003677
IEA
Genome ProjectDNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0015629
IDA
Genome Projectactin cytoskeleton
GO:0005634
IEA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000198Rho GTPase-activating protein domain
IPR001806Small GTPase superfamily
IPR002713FF domain
IPR008936Rho GTPase activation protein
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.