Gene: ENSMUSG00000057329 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000057329
Transcript Identifier
ENSMUST00000112751
Gene Type
Coding gene
Location
1 : 106543264-106712880 : negative

Family Information

Homologous gene family
HOM03P011025
(7 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P065278
(2 genes in 2 species)
specific family

Descriptions

gene_descr
B cell leukemia/lymphoma 2

Identifiers

Type Value
UniprotP10417
MGI88138

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000209
ISO
IEA
Genome Projectprotein polyubiquitination
GO:0000902
IMP
Genome Projectcell morphogenesis
GO:0001503
IMP
Genome Projectossification
GO:0001541
IMP
Genome Projectovarian follicle development
GO:0001656
IMP
Genome Projectmetanephros development
GO:0001657
IMP
Genome Projectureteric bud development
GO:0001658
IDA, IGI
Genome Projectbranching involved in ureteric bud morphogenesis
GO:0001662
IMP
Genome Projectbehavioral fear response
GO:0001776
IMP
Genome Projectleukocyte homeostasis
GO:0001782
IMP
Genome ProjectB cell homeostasis
GO:0001822
IMP, IGI
Genome Projectkidney development
GO:0001836
IDA
Genome Projectrelease of cytochrome c from mitochondria
GO:0001952
IMP
Genome Projectregulation of cell-matrix adhesion
GO:0002260
IMP, IGI
Genome Projectlymphocyte homeostasis
GO:0002320
IMP
Genome Projectlymphoid progenitor cell differentiation
GO:0002326
IMP
Genome ProjectB cell lineage commitment
GO:0002360
IMP
Genome ProjectT cell lineage commitment
GO:0002520
IMP
Genome Projectimmune system development
GO:0002931
IMP
Genome Projectresponse to ischemia
GO:0003014
IMP
Genome Projectrenal system process
GO:0006470
IDA
Genome Projectprotein dephosphorylation
GO:0006582
IMP
Genome Projectmelanin metabolic process
GO:0006808
IGI
Genome Projectregulation of nitrogen utilization
GO:0006874
IDA
Genome Projectcellular calcium ion homeostasis
GO:0006915
IMP
ISO
IEA
Genome Projectapoptotic process
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0006979
IMP
Genome Projectresponse to oxidative stress
GO:0007015
IMP
Genome Projectactin filament organization
GO:0007409
IMP
Genome Projectaxonogenesis
GO:0007569
IMP
Genome Projectcell aging
GO:0008283
IGI
Genome Projectcell proliferation
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0008584
IGI
Genome Projectmale gonad development
GO:0008625
ISO
IEA
Genome Projectextrinsic apoptotic signaling pathway via death domain receptors
GO:0008630
IBA
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008637
IDA
Genome Projectapoptotic mitochondrial changes
GO:0009636
IMP
ISO
IEA
Genome Projectresponse to toxic substance
GO:0009791
IMP, IGI
Genome Projectpost-embryonic development
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0010039
ISO
IEA
Genome Projectresponse to iron ion
GO:0010224
IMP
Genome Projectresponse to UV-B
GO:0010332
IMP
Genome Projectresponse to gamma radiation
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010506
IMP
Genome Projectregulation of autophagy
GO:0010507
IMP
Genome Projectnegative regulation of autophagy
GO:0010523
IGI
Genome Projectnegative regulation of calcium ion transport into cytosol
GO:0010559
IMP
Genome Projectregulation of glycoprotein biosynthetic process
GO:0014031
IMP
Genome Projectmesenchymal cell development
GO:0014042
IMP
Genome Projectpositive regulation of neuron maturation
GO:0014911
IMP
Genome Projectpositive regulation of smooth muscle cell migration
GO:0016049
IMP
Genome Projectcell growth
GO:0016337
IMP
Genome Projectsingle organismal cell-cell adhesion
GO:0018105
IDA
Genome Projectpeptidyl-serine phosphorylation
GO:0018107
IDA
Genome Projectpeptidyl-threonine phosphorylation
GO:0021747
IMP
Genome Projectcochlear nucleus development
GO:0022612
IMP
Genome Projectgland morphogenesis
GO:0022898
ISO
IEA
Genome Projectregulation of transmembrane transporter activity
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030183
IMP
Genome ProjectB cell differentiation
GO:0030217
IMP
Genome ProjectT cell differentiation
GO:0030279
IMP
Genome Projectnegative regulation of ossification
GO:0030307
ISO
IEA
Genome Projectpositive regulation of cell growth
GO:0030308
IMP
Genome Projectnegative regulation of cell growth
GO:0030318
IMP, IGI
Genome Projectmelanocyte differentiation
GO:0030336
IMP
Genome Projectnegative regulation of cell migration
GO:0030890
ISO
IEA
Genome Projectpositive regulation of B cell proliferation
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0031103
IDA
Genome Projectaxon regeneration
GO:0031647
IMP
Genome Projectregulation of protein stability
GO:0032469
IGI
Genome Projectendoplasmic reticulum calcium ion homeostasis
GO:0032835
IMP
Genome Projectglomerulus development
GO:0032848
ISO
IEA
Genome Projectnegative regulation of cellular pH reduction
GO:0032880
IMP
Genome Projectregulation of protein localization
GO:0033033
IDA
Genome Projectnegative regulation of myeloid cell apoptotic process
GO:0033077
IMP
Genome ProjectT cell differentiation in thymus
GO:0033138
IGI
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0033689
IMP
Genome Projectnegative regulation of osteoblast proliferation
GO:0034097
IMP
ISO
IEA
Genome Projectresponse to cytokine
GO:0035094
ISO
IEA
Genome Projectresponse to nicotine
GO:0035265
IMP
Genome Projectorgan growth
GO:0040007
IMP
Genome Projectgrowth
GO:0040018
IMP
Genome Projectpositive regulation of multicellular organism growth
GO:0042100
ISO
IEA
Genome ProjectB cell proliferation
GO:0042149
IDA
Genome Projectcellular response to glucose starvation
GO:0042493
IDA
ISO
IEA
Genome Projectresponse to drug
GO:0042542
IMP
Genome Projectresponse to hydrogen peroxide
GO:0042981
IGI
IEA
Genome Projectregulation of apoptotic process
GO:0043029
IMP, IGI
Genome ProjectT cell homeostasis
GO:0043066
IDA, IMP, IGI
ISS, ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043067
IGI
Genome Projectregulation of programmed cell death
GO:0043085
IMP
Genome Projectpositive regulation of catalytic activity
GO:0043375
IMP
Genome ProjectCD8-positive, alpha-beta T cell lineage commitment
GO:0043473
IMP
Genome Projectpigmentation
GO:0043496
ISO
IEA
Genome Projectregulation of protein homodimerization activity
GO:0043497
ISO
IEA
Genome Projectregulation of protein heterodimerization activity
GO:0043524
IDA, IMP
ISO
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0043583
IMP, IGI
Genome Projectear development
GO:0045069
IDA
Genome Projectregulation of viral genome replication
GO:0045636
IMP
Genome Projectpositive regulation of melanocyte differentiation
GO:0045930
IDA
Genome Projectnegative regulation of mitotic cell cycle
GO:0046671
IMP
Genome Projectnegative regulation of retinal cell programmed cell death
GO:0046902
IDA
Genome Projectregulation of mitochondrial membrane permeability
GO:0048041
IMP
Genome Projectfocal adhesion assembly
GO:0048066
IMP, IGI
Genome Projectdevelopmental pigmentation
GO:0048070
IGI
Genome Projectregulation of developmental pigmentation
GO:0048087
IMP, IGI
Genome Projectpositive regulation of developmental pigmentation
GO:0048536
IMP, IGI
Genome Projectspleen development
GO:0048538
IMP, IGI
Genome Projectthymus development
GO:0048545
IMP
Genome Projectresponse to steroid hormone
GO:0048546
IMP
Genome Projectdigestive tract morphogenesis
GO:0048589
IMP
Genome Projectdevelopmental growth
GO:0048599
IMP
Genome Projectoocyte development
GO:0048743
IMP
Genome Projectpositive regulation of skeletal muscle fiber development
GO:0048753
IMP
Genome Projectpigment granule organization
GO:0048873
IMP
Genome Projecthomeostasis of number of cells within a tissue
GO:0050790
IMP
Genome Projectregulation of catalytic activity
GO:0050853
ISO
IEA
Genome ProjectB cell receptor signaling pathway
GO:0051384
IDA, IMP
Genome Projectresponse to glucocorticoid
GO:0051402
IMP, IGI
Genome Projectneuron apoptotic process
GO:0051607
ISO
IEA
Genome Projectdefense response to virus
GO:0051726
IMP
Genome Projectregulation of cell cycle
GO:0051881
IDA
Genome Projectregulation of mitochondrial membrane potential
GO:0051924
ISO
IEA
Genome Projectregulation of calcium ion transport
GO:0055085
ISO
IEA
Genome Projecttransmembrane transport
GO:0070059
ISS
IEA
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071310
IDA
Genome Projectcellular response to organic substance
GO:0071456
IDA
Genome Projectcellular response to hypoxia
GO:0072593
IMP
Genome Projectreactive oxygen species metabolic process
GO:0097192
IGI
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:2000134
IDA, IMP
Genome Projectnegative regulation of G1/S transition of mitotic cell cycle
GO:2000378
IMP
Genome Projectnegative regulation of reactive oxygen species metabolic process
GO:2000811
ISO
IEA
Genome Projectnegative regulation of anoikis
GO:2001234
IDA
ISO
IEA
Genome Projectnegative regulation of apoptotic signaling pathway
GO:2001240
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243
ISO, IBA
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
ISO
IEA
Genome Projectprotease binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0015267
ISO
IEA
Genome Projectchannel activity
GO:0016248
ISO
IEA
Genome Projectchannel inhibitor activity
GO:0019903
IDA
Genome Projectprotein phosphatase binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0042803
ISO, IBA
IEA
Genome Projectprotein homodimerization activity
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046982
IPI
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0051434
ISO
IEA
Genome ProjectBH3 domain binding
GO:0051721
IDA
Genome Projectprotein phosphatase 2A binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
Genome Projectintracellular
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISO
IEA
Genome Projectmitochondrion
GO:0005741
ISO, IBA
IEA
Genome Projectmitochondrial outer membrane
GO:0005783
IDA
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IDA
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005829
IDA
Genome Projectcytosol
GO:0016020
IDA
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031965
IDA
ISO
IEA
Genome Projectnuclear membrane
GO:0031966
IDA
Genome Projectmitochondrial membrane
GO:0043209
IDA
Genome Projectmyelin sheath
GO:0046930
ISO
IEA
Genome Projectpore complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002475Bcl2-like
IPR003093Apoptosis regulator, Bcl-2 protein, BH4
IPR004725Apoptosis regulator, Bcl-2/ BclX
IPR013278Apoptosis regulator, Bcl-2
IPR020717Apoptosis regulator, Bcl-2, BH1 motif, conserved site
IPR020726Apoptosis regulator, Bcl-2, BH2 motif, conserved site
IPR020728Apoptosis regulator, Bcl-2, BH3 motif, conserved site
IPR020731Apoptosis regulator, Bcl-2, BH4 motif, conserved site
IPR026298Blc2 family

No MapMan annotations defined for this gene.