Gene: ENSMUSG00000057177 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000057177
Transcript Identifier
ENSMUST00000071739
Gene Type
Coding gene
Location
7 : 25228854-25237660 : negative

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000108
(79 genes in 38 species)
specific family

Descriptions

gene_descr
glycogen synthase kinase 3 alpha

Identifiers

Type Value
UniprotQ2NL51
MGI2152453

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003073
IMP
Genome Projectregulation of systemic arterial blood pressure
GO:0003214
IMP
Genome Projectcardiac left ventricle morphogenesis
GO:0005975
IEA
Genome Projectcarbohydrate metabolic process
GO:0005977
IEA
Genome Projectglycogen metabolic process
GO:0006349
IMP
Genome Projectregulation of gene expression by genetic imprinting
GO:0006468
IDA, IMP
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007399
IEA
Genome Projectnervous system development
GO:0008286
IDA
Genome Projectinsulin receptor signaling pathway
GO:0009968
IEA
Genome Projectnegative regulation of signal transduction
GO:0010800
IDA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0016310
IEA
Genome Projectphosphorylation
GO:0016477
IGI
Genome Projectcell migration
GO:0030819
IMP
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0032007
IMP
Genome Projectnegative regulation of TOR signaling
GO:0032869
ISO
IEA
Genome Projectcellular response to insulin stimulus
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0036016
IDA
Genome Projectcellular response to interleukin-3
GO:0043161
IDA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044027
IMP
Genome Projecthypermethylation of CpG island
GO:0045823
IMP
Genome Projectpositive regulation of heart contraction
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046325
ISO
IEA
Genome Projectnegative regulation of glucose import
GO:0046627
ISO
IEA
Genome Projectnegative regulation of insulin receptor signaling pathway
GO:0051348
IEA
Genome Projectnegative regulation of transferase activity
GO:0061052
IMP
Genome Projectnegative regulation of cell growth involved in cardiac muscle cell development
GO:0071285
IDA
Genome Projectcellular response to lithium ion
GO:0071407
IDA
Genome Projectcellular response to organic cyclic compound
GO:0071879
IMP
Genome Projectpositive regulation of adrenergic receptor signaling pathway
GO:0097192
IDA
Genome Projectextrinsic apoptotic signaling pathway in absence of ligand
GO:1901030
IDA
Genome Projectpositive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1903146
ISO
Genome Projectregulation of mitophagy
GO:1903955
ISO
Genome Projectpositive regulation of protein targeting to mitochondrion
GO:1904227
ISO
Genome Projectnegative regulation of glycogen synthase activity, transferring glucose-1-phosphate
GO:2000467
IMP
Genome Projectpositive regulation of glycogen (starch) synthase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA, IMP
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0034236
ISO
IEA
Genome Projectprotein kinase A catalytic subunit binding
GO:0050321
IEA
Genome Projecttau-protein kinase activity

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.