Gene: ENSMUSG00000057113 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000057113
Transcript Identifier
ENSMUST00000075641
Gene Type
Coding gene
Location
11 : 33152814-33162979 : negative

Family Information

Homologous gene family
HOM03P022004
(4 genes in 1 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
nucleophosmin 1

Identifiers

Type Value
UniprotQ61937
UniprotQ5SQB7
MGI106184

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000055
IMP
Genome Projectribosomal large subunit export from nucleus
GO:0000056
IDA
Genome Projectribosomal small subunit export from nucleus
GO:0006281
ISS, ISO
Genome ProjectDNA repair
GO:0006334
ISO
Genome Projectnucleosome assembly
GO:0006407
IDA, IMP
Genome ProjectrRNA export from nucleus
GO:0006884
IDA, IMP
Genome Projectcell volume homeostasis
GO:0006913
IDA
ISO
Genome Projectnucleocytoplasmic transport
GO:0007098
ISS, ISO
Genome Projectcentrosome cycle
GO:0007569
ISS, ISO
Genome Projectcell aging
GO:0008104
IMP
ISO
Genome Projectprotein localization
GO:0008284
IDA, IMP
Genome Projectpositive regulation of cell proliferation
GO:0008285
ISS, ISO
Genome Projectnegative regulation of cell proliferation
GO:0010824
IMP
Genome Projectregulation of centrosome duplication
GO:0010825
IGI
Genome Projectpositive regulation of centrosome duplication
GO:0010826
ISO
Genome Projectnegative regulation of centrosome duplication
GO:0016049
IDA
Genome Projectcell growth
GO:0031328
IDA, IMP
Genome Projectpositive regulation of cellular biosynthetic process
GO:0032071
ISS, ISO
Genome Projectregulation of endodeoxyribonuclease activity
GO:0042273
IDA, IMP
Genome Projectribosomal large subunit biogenesis
GO:0042274
IDA, IMP
Genome Projectribosomal small subunit biogenesis
GO:0043066
ISS, ISO
Genome Projectnegative regulation of apoptotic process
GO:0043085
IEA
Genome Projectpositive regulation of catalytic activity
GO:0043516
IGI
Genome Projectregulation of DNA damage response, signal transduction by p53 class mediator
GO:0043523
IEA
Genome Projectregulation of neuron apoptotic process
GO:0044387
ISS, ISO
Genome Projectnegative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045727
ISS, ISO
Genome Projectpositive regulation of translation
GO:0045740
IEA
Genome Projectpositive regulation of DNA replication
GO:0045860
IDA
Genome Projectpositive regulation of protein kinase activity
GO:0046599
ISS, ISO
Genome Projectregulation of centriole replication
GO:0048025
IDA
Genome Projectnegative regulation of mRNA splicing, via spliceosome
GO:0051054
IEA
Genome Projectpositive regulation of DNA metabolic process
GO:0051092
ISO
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051259
ISO
Genome Projectprotein oligomerization
GO:0051260
IDA
IEA
Genome Projectprotein homooligomerization
GO:0051726
IMP
Genome Projectregulation of cell cycle
GO:0060699
ISS, ISO
Genome Projectregulation of endoribonuclease activity
GO:0060735
ISS, ISO
Genome Projectregulation of eIF2 alpha phosphorylation by dsRNA
GO:1904030
ISO
Genome Projectnegative regulation of cyclin-dependent protein kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003713
ISO
Genome Projecttranscription coactivator activity
GO:0003723
IDA
ISO
IEA
Genome ProjectRNA binding
GO:0004860
ISS, ISO
Genome Projectprotein kinase inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005547
IEA
Genome Projectphosphatidylinositol-3,4,5-trisphosphate binding
GO:0019843
IDA
Genome ProjectrRNA binding
GO:0019899
IEA
Genome Projectenzyme binding
GO:0019901
ISO
Genome Projectprotein kinase binding
GO:0030957
ISO
Genome ProjectTat protein binding
GO:0042393
ISO
Genome Projecthistone binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity
GO:0043023
ISO
Genome Projectribosomal large subunit binding
GO:0043024
ISO
Genome Projectribosomal small subunit binding
GO:0044822
ISO
Genome Projectpoly(A) RNA binding
GO:0046982
ISO
Genome Projectprotein heterodimerization activity
GO:0047485
IPI
Genome Projectprotein N-terminus binding
GO:0051059
ISS, ISO
Genome ProjectNF-kappaB binding
GO:0051082
ISS, ISO
Genome Projectunfolded protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001652
IDA
Genome Projectgranular component
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
IDA
ISO
IEA
Genome Projectnucleoplasm
GO:0005730
IDA
ISO
IEA
Genome Projectnucleolus
GO:0005737
IDA
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0005813
IDA
ISS, ISO
Genome Projectcentrosome
GO:0005829
IDA
Genome Projectcytosol
GO:0005925
ISO
Genome Projectfocal adhesion
GO:0015934
IDA
Genome Projectlarge ribosomal subunit
GO:0015935
IDA
Genome Projectsmall ribosomal subunit
GO:0016020
ISO
Genome Projectmembrane
GO:0016607
IDA
Genome Projectnuclear speck
GO:0030529
ISO
Genome Projectintracellular ribonucleoprotein complex
GO:0031616
ISO
Genome Projectspindle pole centrosome
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005856
IEA
Genome Projectcytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004301Nucleoplasmin family
IPR024057Nucleoplasmin core domain
IPR032569Nucleophosmin, C-terminal

No MapMan annotations defined for this gene.