Gene: ENSMUSG00000055737 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000055737
Transcript Identifier
ENSMUST00000161561
Gene Type
Coding gene
Location
15 : 3319742-3457999 : negative

Family Information

Homologous gene family
HOM03P026495
(3 genes in 2 species)
specific family

Descriptions

gene_descr
growth hormone receptor

Identifiers

Type Value
UniprotQ3UP14
MGI95708

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IEA
Genome Projectactivation of MAPK activity
GO:0007259
IEA
Genome ProjectJAK-STAT cascade
GO:0009725
IEA
Genome Projectresponse to hormone
GO:0009755
IEA
Genome Projecthormone-mediated signaling pathway
GO:0019221
IDA
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0032094
IEA
Genome Projectresponse to food
GO:0032355
ISO
Genome Projectresponse to estradiol
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0032870
ISO
Genome Projectcellular response to hormone stimulus
GO:0034097
IEA
Genome Projectresponse to cytokine
GO:0040018
ISO
Genome Projectpositive regulation of multicellular organism growth
GO:0042976
IEA
Genome Projectactivation of Janus kinase activity
GO:0042977
IEA
Genome Projectactivation of JAK2 kinase activity
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0043434
IEA
Genome Projectresponse to peptide hormone
GO:0044236
ISO
Genome Projectmulticellular organismal metabolic process
GO:0045597
IEA
Genome Projectpositive regulation of cell differentiation
GO:0046427
IEA
Genome Projectpositive regulation of JAK-STAT cascade
GO:0048009
ISO
Genome Projectinsulin-like growth factor receptor signaling pathway
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0060351
IEA
Genome Projectcartilage development involved in endochondral bone morphogenesis
GO:0060396
ISO
IEA
Genome Projectgrowth hormone receptor signaling pathway
GO:0070555
IEA
Genome Projectresponse to interleukin-1
GO:1901215
IEA
Genome Projectnegative regulation of neuron death

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004896
IEA
Genome Projectcytokine receptor activity
GO:0004903
IDA
IEA
Genome Projectgrowth hormone receptor activity
GO:0017046
IPI
ISO
Genome Projectpeptide hormone binding
GO:0019838
ISO
Genome Projectgrowth factor binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0019903
IEA
Genome Projectprotein phosphatase binding
GO:0042169
IEA
Genome ProjectSH2 domain binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005887
ISO
Genome Projectintegral component of plasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
ISO
Genome Projectintegral component of membrane
GO:0019898
IDA
Genome Projectextrinsic component of membrane
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043235
ISO
Genome Projectreceptor complex
GO:0070195
ISO
Genome Projectgrowth hormone receptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003528Long hematopoietin receptor, single chain, conserved site
IPR003961Fibronectin type III
IPR013783Immunoglobulin-like fold
IPR015152Growth hormone/erythropoietin receptor, ligand binding
IPR025871Growth hormone-binding protein

No MapMan annotations defined for this gene.