Gene: ENSMUSG00000054640 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000054640
Transcript Identifier
ENSMUST00000086538
Gene Type
Coding gene
Location
17 : 81388691-81649607 : negative

Family Information

Homologous gene family
HOM03P004521
(21 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P006907
(12 genes in 8 species)
specific family

Descriptions

gene_descr
solute carrier family 8 (sodium/calcium exchanger), member 1

Identifiers

Type Value
UniprotG3X9J1
MGI107956

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001892
IMP
Genome Projectembryonic placenta development
GO:0002026
IMP
Genome Projectregulation of the force of heart contraction
GO:0002028
IEA
Genome Projectregulation of sodium ion transport
GO:0003007
IGI
Genome Projectheart morphogenesis
GO:0006814
IDA
IEA
Genome Projectsodium ion transport
GO:0006816
IDA, IMP
IEA
Genome Projectcalcium ion transport
GO:0006874
IEA
Genome Projectcellular calcium ion homeostasis
GO:0006883
ISO
IEA
Genome Projectcellular sodium ion homeostasis
GO:0007154
IEA
Genome Projectcell communication
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0009749
IEA
Genome Projectresponse to glucose
GO:0009791
IGI
Genome Projectpost-embryonic development
GO:0010763
IEA
Genome Projectpositive regulation of fibroblast migration
GO:0010881
IEA
Genome Projectregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0021537
IEA
Genome Projecttelencephalon development
GO:0030501
ISO
Genome Projectpositive regulation of bone mineralization
GO:0033198
IEA
Genome Projectresponse to ATP
GO:0034614
ISO
IEA
Genome Projectcellular response to reactive oxygen species
GO:0035050
IMP
Genome Projectembryonic heart tube development
GO:0035725
ISO
Genome Projectsodium ion transmembrane transport
GO:0035902
IEA
Genome Projectresponse to immobilization stress
GO:0035994
ISO
IEA
Genome Projectresponse to muscle stretch
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0048747
IGI
Genome Projectmuscle fiber development
GO:0051924
IEA
Genome Projectregulation of calcium ion transport
GO:0055013
IMP
Genome Projectcardiac muscle cell development
GO:0055085
IEA
Genome Projecttransmembrane transport
GO:0060048
IGI
Genome Projectcardiac muscle contraction
GO:0060402
IEA
Genome Projectcalcium ion transport into cytosol
GO:0070509
ISO
IEA
Genome Projectcalcium ion import
GO:0070588
ISO
IEA
Genome Projectcalcium ion transmembrane transport
GO:0071320
IEA
Genome Projectcellular response to cAMP
GO:0071436
ISO
IEA
Genome Projectsodium ion export
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0086064
IEA
Genome Projectcell communication by electrical coupling involved in cardiac conduction
GO:0097369
ISO
IEA
Genome Projectsodium ion import
GO:0098735
ISO
IEA
Genome Projectpositive regulation of the force of heart contraction
GO:1901660
ISO
IEA
Genome Projectcalcium ion export

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005432
IDA
ISO
IEA
Genome Projectcalcium:sodium antiporter activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008092
ISO
IEA
Genome Projectcytoskeletal protein binding
GO:0030506
ISO
Genome Projectankyrin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
IEA
Genome Projectcytosol
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005887
ISO
IEA
Genome Projectintegral component of plasma membrane
GO:0014704
IEA
Genome Projectintercalated disc
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
TAS, IEA
Genome Projectintegral component of membrane
GO:0016323
IDA
Genome Projectbasolateral plasma membrane
GO:0030018
IEA
Genome ProjectZ disc
GO:0030315
IDA
Genome ProjectT-tubule
GO:0042383
IDA
IEA
Genome Projectsarcolemma
GO:0042995
IEA
Genome Projectcell projection
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043198
IEA
Genome Projectdendritic shaft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001623DnaJ domain
IPR002987Sodium/calcium exchanger, isoform 1
IPR003644Na-Ca exchanger/integrin-beta4
IPR004836Sodium/calcium exchanger protein
IPR004837Sodium/calcium exchanger membrane region
IPR032452Sodium/calcium exchanger domain, C-terminal extension

No MapMan annotations defined for this gene.