Gene: ENSMUSG00000053754 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000053754
Transcript Identifier
ENSMUST00000089752
Gene Type
Coding gene
Location
14 : 52198592-52237572 : negative

Family Information

Homologous gene family
HOM03P000018
(1093 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001645
(36 genes in 24 species)
specific family

Descriptions

gene_descr
chromodomain helicase DNA binding protein 8

Identifiers

Type Value
UniprotQ09XV5
MGI1915022

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007420
ISO
Genome Projectbrain development
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0016568
IEA
Genome Projectchromatin modification
GO:0030178
ISS, ISO
Genome Projectnegative regulation of Wnt signaling pathway
GO:0032508
ISO
Genome ProjectDNA duplex unwinding
GO:0043044
ISS, ISO
Genome ProjectATP-dependent chromatin remodeling
GO:0043066
IDA, IMP
Genome Projectnegative regulation of apoptotic process
GO:0045892
IDA
ISO
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
ISS, ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISS, ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0045945
ISS, ISO
Genome Projectpositive regulation of transcription from RNA polymerase III promoter
GO:0048565
ISO
Genome Projectdigestive tract development
GO:0060070
ISS, ISO
Genome Projectcanonical Wnt signaling pathway
GO:0090090
ISO
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:2000270
IDA
Genome Projectnegative regulation of fibroblast apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0002039
IPI
Genome Projectp53 binding
GO:0003677
IDA
ISS, ISO
IEA
Genome ProjectDNA binding
GO:0003678
ISS, ISO
Genome ProjectDNA helicase activity
GO:0003682
ISO
Genome Projectchromatin binding
GO:0004386
IEA
Genome Projecthelicase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
ISS, ISO
IEA
Genome ProjectATP binding
GO:0008013
ISS, ISO
Genome Projectbeta-catenin binding
GO:0008094
ISS, ISO
Genome ProjectDNA-dependent ATPase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016817
IEA
Genome Projecthydrolase activity, acting on acid anhydrides
GO:0035064
ISS, ISO
Genome Projectmethylated histone binding
GO:0042393
IDA, IPI
Genome Projecthistone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0043234
ISO
Genome Projectprotein complex
GO:0071339
ISS, ISO
Genome ProjectMLL1 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000330SNF2-related, N-terminal domain
IPR000953Chromo/chromo shadow domain
IPR001650Helicase, C-terminal
IPR006576BRK domain
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR016197Chromo domain-like
IPR023780Chromo domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.