Gene: ENSMUSG00000052430 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000052430
Transcript Identifier
ENSMUST00000106230
Gene Type
Coding gene
Location
3 : 141840615-141880499 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P015166
(6 genes in 4 species)
specific family

Descriptions

gene_descr
bone morphogenetic protein receptor, type 1B

Identifiers

Type Value
UniprotP36898
UniprotB2RRZ4
MGI107191

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001501
ISO
IEA
Genome Projectskeletal system development
GO:0001502
IMP
Genome Projectcartilage condensation
GO:0001654
IMP
Genome Projecteye development
GO:0002062
IMP, IGI
Genome Projectchondrocyte differentiation
GO:0002063
ISS
Genome Projectchondrocyte development
GO:0006468
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007178
IGI
IEA
Genome Projecttransmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007179
TAS
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0009953
IGI
Genome Projectdorsal/ventral pattern formation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0023014
IEA
Genome Projectsignal transduction by protein phosphorylation
GO:0030154
IMP, IGI
Genome Projectcell differentiation
GO:0030166
ISS
Genome Projectproteoglycan biosynthetic process
GO:0030501
ISO
IEA
Genome Projectpositive regulation of bone mineralization
GO:0030509
IMP, IGI
ISO
Genome ProjectBMP signaling pathway
GO:0031290
IMP
Genome Projectretinal ganglion cell axon guidance
GO:0035108
ISO
IEA
Genome Projectlimb morphogenesis
GO:0043010
IGI
Genome Projectcamera-type eye development
GO:0045597
ISO
IEA
Genome Projectpositive regulation of cell differentiation
GO:0045669
ISO
IEA
Genome Projectpositive regulation of osteoblast differentiation
GO:0045944
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0060041
IMP
Genome Projectretina development in camera-type eye
GO:0060350
ISS
Genome Projectendochondral bone morphogenesis
GO:0061036
ISS
Genome Projectpositive regulation of cartilage development
GO:0071773
ISO
Genome Projectcellular response to BMP stimulus
GO:1902043
IGI
Genome Projectpositive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902731
ISS
Genome Projectnegative regulation of chondrocyte proliferation
GO:0001550
IMP
Genome Projectovarian cumulus expansion
GO:0006703
NAS
Genome Projectestrogen biosynthetic process
GO:0006954
IEP
Genome Projectinflammatory response
GO:0042698
IMP
Genome Projectovulation cycle
GO:0051216
IEA
Genome Projectcartilage development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0001948
ISO
Genome Projectglycoprotein binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004675
ISO
IEA
Genome Projecttransmembrane receptor protein serine/threonine kinase activity
GO:0004702
IEA
Genome Projectreceptor signaling protein serine/threonine kinase activity
GO:0005024
TAS
Genome Projecttransforming growth factor beta-activated receptor activity
GO:0005025
IMP
Genome Projecttransforming growth factor beta receptor activity, type I
GO:0005524
ISO
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0046332
ISO
IEA
Genome ProjectSMAD binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030425
IEA
Genome Projectdendrite
GO:0043025
IEA
Genome Projectneuronal cell body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000333Ser/Thr protein kinase, TGFB receptor
IPR000472Activin types I and II receptor domain
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR003605GS domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.