Gene: ENSMUSG00000052397 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000052397
Transcript Identifier
ENSMUST00000064234
Gene Type
Coding gene
Location
17 : 6739303-6782643 : negative

Family Information

Homologous gene family
HOM03P007566
(11 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P010170
(8 genes in 4 species)
specific family

Descriptions

gene_descr
ezrin

Identifiers

Type Value
UniprotP26040
UniprotQ4KML7
MGI98931

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001951
IGI
Genome Projectintestinal D-glucose absorption
GO:0003376
ISO
Genome Projectsphingosine-1-phosphate signaling pathway
GO:0007159
IEA
Genome Projectleukocyte cell-cell adhesion
GO:0008360
IEA
Genome Projectregulation of cell shape
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010737
ISO
Genome Projectprotein kinase A signaling
GO:0022614
IEA
Genome Projectmembrane to membrane docking
GO:0030855
IEA
Genome Projectepithelial cell differentiation
GO:0031532
ISO
Genome Projectactin cytoskeleton reorganization
GO:0031623
IMP
Genome Projectreceptor internalization
GO:0032532
IGI
Genome Projectregulation of microvillus length
GO:0035088
IMP
Genome Projectestablishment or maintenance of apical/basal cell polarity
GO:0040018
IGI
Genome Projectpositive regulation of multicellular organism growth
GO:0046847
ISO
IEA
Genome Projectfilopodium assembly
GO:0048015
ISO
Genome Projectphosphatidylinositol-mediated signaling
GO:0050714
ISO
Genome Projectpositive regulation of protein secretion
GO:0050852
ISO
Genome ProjectT cell receptor signaling pathway
GO:0051017
ISS, ISO
IEA
Genome Projectactin filament bundle assembly
GO:0061028
ISO
IEA
Genome Projectestablishment of endothelial barrier
GO:0071320
ISO
Genome Projectcellular response to cAMP
GO:0072697
ISO
Genome Projectprotein localization to cell cortex
GO:0090002
ISO
Genome Projectestablishment of protein localization to plasma membrane
GO:0090004
IGI
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:1900041
ISO
Genome Projectnegative regulation of interleukin-2 secretion
GO:1902115
ISO
Genome Projectregulation of organelle assembly
GO:1902896
IGI
Genome Projectterminal web assembly
GO:1902966
ISO
Genome Projectpositive regulation of protein localization to early endosome
GO:1903364
ISO
Genome Projectpositive regulation of cellular protein catabolic process
GO:2000643
ISO
Genome Projectpositive regulation of early endosome to late endosome transport
GO:0030033
IGI
IEA
Genome Projectmicrovillus assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008017
ISO
Genome Projectmicrotubule binding
GO:0008092
IEA
Genome Projectcytoskeletal protein binding
GO:0019904
ISO
IEA
Genome Projectprotein domain specific binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0034236
ISO
Genome Projectprotein kinase A catalytic subunit binding
GO:0034237
ISO
Genome Projectprotein kinase A regulatory subunit binding
GO:0044548
ISO
Genome ProjectS100 protein binding
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding
GO:0050839
ISS, ISO
IEA
Genome Projectcell adhesion molecule binding
GO:0051015
ISS, ISO
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001726
ISO
IEA
Genome Projectruffle
GO:0001931
IDA
Genome Projecturopod
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005622
IDA
Genome Projectintracellular
GO:0005730
ISO
IEA
Genome Projectnucleolus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005768
ISO
Genome Projectendosome
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005884
ISS, ISO
IEA
Genome Projectactin filament
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0005902
IDA
ISO
IEA
Genome Projectmicrovillus
GO:0005903
IDA
Genome Projectbrush border
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0005938
IEA
Genome Projectcell cortex
GO:0015629
ISS, ISO
IEA
Genome Projectactin cytoskeleton
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016323
ISS
IEA
Genome Projectbasolateral plasma membrane
GO:0016324
IDA
ISO
IEA
Genome Projectapical plasma membrane
GO:0019898
ISS, ISO
IEA
Genome Projectextrinsic component of membrane
GO:0030175
ISO
IEA
Genome Projectfilopodium
GO:0030315
IEA
Genome ProjectT-tubule
GO:0031528
IEA
Genome Projectmicrovillus membrane
GO:0031982
ISO
IEA
Genome Projectvesicle
GO:0032587
IEA
Genome Projectruffle membrane
GO:0036064
IDA
Genome Projectciliary basal body
GO:0042995
ISO
IEA
Genome Projectcell projection
GO:0043209
IDA
Genome Projectmyelin sheath
GO:0044297
IEA
Genome Projectcell body
GO:0044393
IEA
Genome Projectmicrospike
GO:0044853
ISO
Genome Projectplasma membrane raft
GO:0045121
IEA
Genome Projectmembrane raft
GO:0045177
IDA
ISO
IEA
Genome Projectapical part of cell
GO:0048471
ISO
Genome Projectperinuclear region of cytoplasm
GO:0051286
IEA
Genome Projectcell tip
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0071944
ISO
IEA
Genome Projectcell periphery
GO:0097449
IEA
Genome Projectastrocyte projection
GO:0097454
IEA
Genome ProjectSchwann cell microvillus
GO:0098592
ISO
Genome Projectcytoplasmic side of apical plasma membrane
GO:0001772
ISO
Genome Projectimmunological synapse

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000299FERM domain
IPR000798Ezrin/radixin/moesin-like
IPR008954Moesin tail domain
IPR011174Ezrin/radixin/moesin
IPR011259Ezrin/radixin/moesin, C-terminal
IPR011993PH domain-like
IPR014352FERM/acyl-CoA-binding protein, 3-helical bundle
IPR018979FERM, N-terminal
IPR018980FERM, C-terminal PH-like domain
IPR019747FERM conserved site
IPR019748FERM central domain
IPR019749Band 4.1 domain
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.