Gene: ENSMUSG00000050541 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000050541
Transcript Identifier
ENSMUST00000167574
Gene Type
Coding gene
Location
11 : 43775861-43836088 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P067297
(2 genes in 2 species)
specific family

Descriptions

gene_descr
adrenergic receptor, alpha 1b

Identifiers

Type Value
UniprotQ9DBL0
MGI104774

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001974
IMP
Genome Projectblood vessel remodeling
GO:0001975
IMP
Genome Projectresponse to amphetamine
GO:0001987
IMP
Genome Projectvasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure
GO:0001994
IBA
Genome Projectnorepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0001996
IGI
Genome Projectpositive regulation of heart rate by epinephrine-norepinephrine
GO:0001997
IGI
Genome Projectpositive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0006937
IEA
Genome Projectregulation of muscle contraction
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007200
IBA
Genome Projectphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204
IBA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0007512
IGI
Genome Projectadult heart development
GO:0007626
IMP
Genome Projectlocomotory behavior
GO:0008542
IMP
Genome Projectvisual learning
GO:0016049
IGI
Genome Projectcell growth
GO:0019229
IEA
Genome Projectregulation of vasoconstriction
GO:0035024
ISO
Genome Projectnegative regulation of Rho protein signal transduction
GO:0035265
IGI
Genome Projectorgan growth
GO:0042593
IMP
Genome Projectglucose homeostasis
GO:0043278
IMP
Genome Projectresponse to morphine
GO:0043410
ISO
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0045818
IMP
Genome Projectnegative regulation of glycogen catabolic process
GO:0045819
IMP
Genome Projectpositive regulation of glycogen catabolic process
GO:0045907
IBA
Genome Projectpositive regulation of vasoconstriction
GO:0045987
IBA
Genome Projectpositive regulation of smooth muscle contraction
GO:0048148
IMP
Genome Projectbehavioral response to cocaine
GO:0055117
IEA
Genome Projectregulation of cardiac muscle contraction
GO:0071880
IBA
Genome Projectadenylate cyclase-activating adrenergic receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004935
IEA
Genome Projectadrenergic receptor activity
GO:0004937
IDA, IMP, IGI
IEA
Genome Projectalpha1-adrenergic receptor activity
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005829
IBA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
IBA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IDA
IEA
Genome Projectintegral component of membrane
GO:0031965
ISO
IEA
Genome Projectnuclear membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR001115Alpha 1B adrenoceptor
IPR002233Adrenoceptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.