Gene: ENSMUSG00000050440 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000050440
Transcript Identifier
ENSMUST00000062620
Gene Type
Coding gene
Location
7 : 30942477-30943983 : negative

Family Information

Homologous gene family
HOM03P045781
(2 genes in 1 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
hepcidin antimicrobial peptide

Identifiers

Type Value
UniprotQ9EQ21
MGI1933533

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0002262
IMP
Genome Projectmyeloid cell homeostasis
GO:0006879
IDA
IEA
Genome Projectcellular iron ion homeostasis
GO:0007259
IDA
Genome ProjectJAK-STAT cascade
GO:0031668
TAS
Genome Projectcellular response to extracellular stimulus
GO:0033619
IDA
Genome Projectmembrane protein proteolysis
GO:0034760
IDA, IGI
Genome Projectnegative regulation of iron ion transmembrane transport
GO:0042742
IDA, IMP
Genome Projectdefense response to bacterium
GO:0043032
IMP
Genome Projectpositive regulation of macrophage activation
GO:0045779
IMP
Genome Projectnegative regulation of bone resorption
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050728
IGI
Genome Projectnegative regulation of inflammatory response
GO:0050832
IDA
Genome Projectdefense response to fungus
GO:0055072
IDA, IMP
Genome Projectiron ion homeostasis
GO:0071281
TAS
Genome Projectcellular response to iron ion
GO:1903364
IDA
Genome Projectpositive regulation of cellular protein catabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005179
IBA
IEA
Genome Projecthormone activity
GO:0005507
IDA
Genome Projectcopper ion binding
GO:0097690
IBA
Genome Projectiron channel inhibitor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IDA
IEA
Genome Projectextracellular region
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IDA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR010500Hepcidin

No MapMan annotations defined for this gene.