Gene: ENSMUSG00000049791 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000049791
Transcript Identifier
ENSMUST00000058755
Gene Type
Coding gene
Location
7 : 89404687-89408360 : positive

Family Information

Homologous gene family
HOM03P002165
(40 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P011849
(7 genes in 3 species)
specific family

Descriptions

gene_descr
frizzled homolog 4 (Drosophila)

Identifiers

Type Value
UniprotQ61088
UniprotQ3V1B2
MGI108520

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001553
IMP
Genome Projectluteinization
GO:0001568
IMP
Genome Projectblood vessel development
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0007186
IBA
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007223
ISO
IEA
Genome ProjectWnt signaling pathway, calcium modulating pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0010812
IMP
ISO
IEA
Genome Projectnegative regulation of cell-substrate adhesion
GO:0016055
ISO
IEA
Genome ProjectWnt signaling pathway
GO:0030947
IMP
Genome Projectregulation of vascular endothelial growth factor receptor signaling pathway
GO:0031987
IMP
Genome Projectlocomotion involved in locomotory behavior
GO:0034446
IMP
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0035567
IBA
Genome Projectnon-canonical Wnt signaling pathway
GO:0042701
IMP
Genome Projectprogesterone secretion
GO:0043507
IGI
Genome Projectpositive regulation of JUN kinase activity
GO:0045893
IDA
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0051091
IDA
ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0060070
IDA, IGI
ISO
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0061299
IMP, IGI
ISO
IEA
Genome Projectretina vasculature morphogenesis in camera-type eye
GO:0007165
IEA
Genome Projectsignal transduction
GO:0035426
IDA
Genome Projectextracellular matrix-cell signaling
GO:0061301
IMP
Genome Projectcerebellum vasculature morphogenesis
GO:0061304
IMP
Genome Projectretinal blood vessel morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004888
IEA
Genome Projecttransmembrane signaling receptor activity
GO:0004930
IBA
IEA
Genome ProjectG-protein coupled receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017147
IPI
IEA
Genome ProjectWnt-protein binding
GO:0019955
IPI
ISO
IEA
Genome Projectcytokine binding
GO:0030165
ISO
IEA
Genome ProjectPDZ domain binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0042813
IPI
ISO
IEA
Genome ProjectWnt-activated receptor activity
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0004871
IEA
Genome Projectsignal transducer activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IDA, IMP
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IBA
IEA
Genome Projectintegral component of membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000539Frizzled protein
IPR015526Frizzled/secreted frizzled-related protein
IPR017981GPCR, family 2-like
IPR020067Frizzled domain
IPR026551Frizzled-4

No MapMan annotations defined for this gene.