Gene: ENSMUSG00000049583 (Mus musculus)

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Gene Identifier
ENSMUSG00000049583
Transcript Identifier
ENSMUST00000167164
Gene Type
Coding gene
Location
7 : 87602544-88130869 : positive

Family Information

Homologous gene family
HOM03P000228
(156 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P004612
(18 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
glutamate receptor, metabotropic 5

Identifiers

Type Value
UniprotQ3UVX5
UniprotB2BH30
MGI1351342

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000185
IEA
Genome Projectactivation of MAPKKK activity
GO:0002029
IEA
Genome Projectdesensitization of G-protein coupled receptor protein signaling pathway
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006468
IEA
Genome Projectprotein phosphorylation
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007205
IBA
IEA
Genome Projectprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007206
TAS
Genome Projectphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
GO:0007216
ISS, ISO
IEA
Genome ProjectG-protein coupled glutamate receptor signaling pathway
GO:0007268
IEA
Genome Projectsynaptic transmission
GO:0007612
IMP
Genome Projectlearning
GO:0007626
IMP, IGI
Genome Projectlocomotory behavior
GO:0040013
IEA
Genome Projectnegative regulation of locomotion
GO:0048169
IMP
Genome Projectregulation of long-term neuronal synaptic plasticity
GO:0048170
IEA
Genome Projectpositive regulation of long-term neuronal synaptic plasticity
GO:0050890
ISO
IEA
Genome Projectcognition
GO:0051966
IBA
Genome Projectregulation of synaptic transmission, glutamatergic

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001639
TAS
Genome ProjectPLC activating G-protein coupled glutamate receptor activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
ISS, ISO
IEA
Genome ProjectG-protein coupled receptor activity
GO:0008066
ISS, ISO
IEA
Genome Projectglutamate receptor activity
GO:0031687
IEA
Genome ProjectA2A adenosine receptor binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0005887
ISS, ISO, IBA
IEA
Genome Projectintegral component of plasma membrane
GO:0014069
IBA
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043198
IEA
Genome Projectdendritic shaft
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0097449
IEA
Genome Projectastrocyte projection
GO:0043005
IDA
Genome Projectneuron projection

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000162GPCR, family 3, metabotropic glutamate receptor
IPR000202GPCR, family 3, metabotropic glutamate receptor 5
IPR000337GPCR, family 3
IPR001828Receptor, ligand binding region
IPR011500GPCR, family 3, nine cysteines domain
IPR017978GPCR family 3, C-terminal
IPR017979GPCR, family 3, conserved site
IPR019588Metabotropic glutamate receptor, Homer-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.