Gene: ENSMUSG00000049115 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000049115
Transcript Identifier
ENSMUST00000066412
Gene Type
Coding gene
Location
13 : 30380954-30382033 : positive

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P049224
(2 genes in 1 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
angiotensin II receptor, type 1a

Identifiers

Type Value
UniprotP29754
MGI87964

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001568
IGI
Genome Projectblood vessel development
GO:0001822
IMP, IGI
ISO
Genome Projectkidney development
GO:0001921
IEA
Genome Projectpositive regulation of receptor recycling
GO:0001991
IGI
Genome Projectregulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0002001
IMP
Genome Projectrenin secretion into blood stream
GO:0002018
IMP
IEA
Genome Projectrenin-angiotensin regulation of aldosterone production
GO:0002019
IMP
Genome Projectregulation of renal output by angiotensin
GO:0002035
IMP
Genome Projectbrain renin-angiotensin system
GO:0006885
IEA
Genome Projectregulation of pH
GO:0006954
IGI
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
ISO
IC, IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007200
IEA
Genome Projectphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204
ISO
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007266
ISO
Genome ProjectRho protein signal transduction
GO:0007507
IMP
Genome Projectheart development
GO:0007568
IEA
Genome Projectaging
GO:0008284
IMP
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010873
ISO
Genome Projectpositive regulation of cholesterol esterification
GO:0019229
ISO
IEA
Genome Projectregulation of vasoconstriction
GO:0019722
ISO
Genome Projectcalcium-mediated signaling
GO:0032270
ISO
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032430
ISO
Genome Projectpositive regulation of phospholipase A2 activity
GO:0032930
IEA
Genome Projectpositive regulation of superoxide anion generation
GO:0034391
IGI
Genome Projectregulation of smooth muscle cell apoptotic process
GO:0034392
IMP
Genome Projectnegative regulation of smooth muscle cell apoptotic process
GO:0038166
ISO
Genome Projectangiotensin-activated signaling pathway
GO:0042310
IEA
Genome Projectvasoconstriction
GO:0042416
IEA
Genome Projectdopamine biosynthetic process
GO:0042756
IMP, IGI
IEA
Genome Projectdrinking behavior
GO:0042976
IEA
Genome Projectactivation of Janus kinase activity
GO:0043627
IEA
Genome Projectresponse to estrogen
GO:0045777
IDA, IMP, IGI
IEA
Genome Projectpositive regulation of blood pressure
GO:0050715
IMP
Genome Projectpositive regulation of cytokine secretion
GO:0051482
ISO
Genome Projectpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0060326
ISO
Genome Projectcell chemotaxis
GO:0071549
IEA
Genome Projectcellular response to dexamethasone stimulus
GO:0086097
ISO
IEA
Genome Projectphospholipase C-activating angiotensin-activated signaling pathway
GO:0090190
IEA
Genome Projectpositive regulation of branching involved in ureteric bud morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001596
IDA
ISO
IEA
Genome Projectangiotensin type I receptor activity
GO:0001965
IEA
Genome ProjectG-protein alpha-subunit binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004945
ISO
IEA
Genome Projectangiotensin type II receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0017046
IEA
Genome Projectpeptide hormone binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0031711
ISO
Genome Projectbradykinin receptor binding
GO:0031748
IEA
Genome ProjectD1 dopamine receptor binding
GO:0043621
IEA
Genome Projectprotein self-association
GO:0046982
ISO
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
ISO
Genome Projectintracellular
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005768
IDA
Genome Projectendosome
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
ISO
Genome Projectcytosol
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0012505
IEA
Genome Projectendomembrane system
GO:0012506
IEA
Genome Projectvesicle membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0030425
IEA
Genome Projectdendrite
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0031968
IEA
Genome Projectorganelle outer membrane
GO:0031983
IEA
Genome Projectvesicle lumen
GO:0055037
IEA
Genome Projectrecycling endosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000190Angiotensin II receptor type 1
IPR000248Angiotensin II receptor family
IPR000276G protein-coupled receptor, rhodopsin-like
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.