Gene: ENSMUSG00000049107 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000049107
Transcript Identifier
ENSMUST00000112244
Gene Type
Coding gene
Location
6 : 126101726-126164747 : negative

Family Information

Homologous gene family
HOM03P010566
(8 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P064839
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
neurotrophin 3

Identifiers

Type Value
UniprotQ3V1A4
MGI97380

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
ISO
IEA
Genome Projectactivation of MAPK activity
GO:0002092
ISO
IEA
Genome Projectpositive regulation of receptor internalization
GO:0007169
ISO, IBA
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007274
IDA
Genome Projectneuromuscular synaptic transmission
GO:0007403
IMP
Genome Projectglial cell fate determination
GO:0007411
IDA, IMP
Genome Projectaxon guidance
GO:0007420
IMP
Genome Projectbrain development
GO:0007422
IMP
Genome Projectperipheral nervous system development
GO:0008284
ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008544
IMP
Genome Projectepidermis development
GO:0021675
IMP
Genome Projectnerve development
GO:0030335
ISO
IEA
Genome Projectpositive regulation of cell migration
GO:0032148
ISO
IEA
Genome Projectactivation of protein kinase B activity
GO:0033138
ISO
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0042490
IGI
Genome Projectmechanoreceptor differentiation
GO:0042981
ISO
Genome Projectregulation of apoptotic process
GO:0043523
IDA
Genome Projectregulation of neuron apoptotic process
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0045664
IBA
Genome Projectregulation of neuron differentiation
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048484
IMP
Genome Projectenteric nervous system development
GO:0048666
IMP
Genome Projectneuron development
GO:0048699
IGI
Genome Projectgeneration of neurons
GO:0048812
IBA
Genome Projectneuron projection morphogenesis
GO:0050731
ISO
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050732
ISO
IEA
Genome Projectnegative regulation of peptidyl-tyrosine phosphorylation
GO:0050918
ISO
IEA
Genome Projectpositive chemotaxis
GO:0050930
ISO
IEA
Genome Projectinduction of positive chemotaxis
GO:0051145
IMP
Genome Projectsmooth muscle cell differentiation
GO:0090630
ISO
IEA
Genome Projectactivation of GTPase activity
GO:2000251
ISO
IEA
Genome Projectpositive regulation of actin cytoskeleton reorganization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005165
IEA
Genome Projectneurotrophin receptor binding
GO:0005166
TAS
Genome Projectneurotrophin p75 receptor binding
GO:0008083
ISO, IBA
IEA
Genome Projectgrowth factor activity
GO:0042056
ISO
IEA
Genome Projectchemoattractant activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002072Nerve growth factor-related
IPR015578Neurotrophin-3
IPR019846Nerve growth factor conserved site
IPR020408Nerve growth factor-like
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.