Gene: ENSMUSG00000048482 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000048482
Transcript Identifier
ENSMUST00000111042
Gene Type
Coding gene
Location
2 : 109709563-109724152 : positive

Family Information

Homologous gene family
HOM03P010566
(8 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P072317
(2 genes in 2 species)
specific family

Descriptions

gene_descr
brain derived neurotrophic factor

Identifiers

Type Value
UniprotH9H9S8
MGI88145

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001657
IDA
Genome Projectureteric bud development
GO:0001662
IMP
Genome Projectbehavioral fear response
GO:0007169
IBA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007214
IDA
Genome Projectgamma-aminobutyric acid signaling pathway
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0007406
IDA
Genome Projectnegative regulation of neuroblast proliferation
GO:0007411
IMP
Genome Projectaxon guidance
GO:0007412
IMP
Genome Projectaxon target recognition
GO:0007416
ISO
Genome Projectsynapse assembly
GO:0007611
IMP
Genome Projectlearning or memory
GO:0007631
IMP
Genome Projectfeeding behavior
GO:0008038
IMP
Genome Projectneuron recognition
GO:0014047
IPI
Genome Projectglutamate secretion
GO:0016358
IMP
Genome Projectdendrite development
GO:0019222
IMP
Genome Projectregulation of metabolic process
GO:0021675
IMP
Genome Projectnerve development
GO:0032229
IDA
Genome Projectnegative regulation of synaptic transmission, GABAergic
GO:0033138
IDA, IMP
ISO
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0042490
IGI
Genome Projectmechanoreceptor differentiation
GO:0042493
IMP
Genome Projectresponse to drug
GO:0042596
IMP
Genome Projectfear response
GO:0043066
IDA
Genome Projectnegative regulation of apoptotic process
GO:0043523
IDA
Genome Projectregulation of neuron apoptotic process
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0045666
IDA
Genome Projectpositive regulation of neuron differentiation
GO:0046668
IDA
Genome Projectregulation of retinal cell programmed cell death
GO:0048167
IDA
Genome Projectregulation of synaptic plasticity
GO:0048668
ISO
Genome Projectcollateral sprouting
GO:0048675
IDA
Genome Projectaxon extension
GO:0048812
IBA
Genome Projectneuron projection morphogenesis
GO:0048839
IMP
Genome Projectinner ear development
GO:0051091
ISO
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0060080
IMP
Genome Projectinhibitory postsynaptic potential
GO:0060548
IMP
Genome Projectnegative regulation of cell death
GO:0061193
IMP
Genome Projecttaste bud development
GO:0097484
IDA
Genome Projectdendrite extension
GO:2000324
ISO
Genome Projectpositive regulation of glucocorticoid receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005169
IBA
Genome Projectneurotrophin TRKB receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
IBA
IEA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016023
IDA
Genome Projectcytoplasmic membrane-bounded vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002072Nerve growth factor-related
IPR019846Nerve growth factor conserved site
IPR020408Nerve growth factor-like
IPR020430Brain-derived neurotrophic factor
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.