Gene: ENSMUSG00000048450 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000048450
Transcript Identifier
ENSMUST00000063116
Gene Type
Coding gene
Location
5 : 37821258-37824333 : negative

Family Information

Homologous gene family
HOM03P000104
(258 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P076265
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
msh homeobox 1

Identifiers

Type Value
UniprotP13297
MGI97168

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IGI
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000902
ISO
IEA
Genome Projectcell morphogenesis
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001837
IMP
Genome Projectepithelial to mesenchymal transition
GO:0003007
IGI
Genome Projectheart morphogenesis
GO:0003198
IGI
Genome Projectepithelial to mesenchymal transition involved in endocardial cushion formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007507
IGI
Genome Projectheart development
GO:0007517
IPI
Genome Projectmuscle organ development
GO:0008285
IGI
Genome Projectnegative regulation of cell proliferation
GO:0009952
IGI
Genome Projectanterior/posterior pattern specification
GO:0010463
IMP
Genome Projectmesenchymal cell proliferation
GO:0023019
IGI
Genome Projectsignal transduction involved in regulation of gene expression
GO:0030308
ISO
IEA
Genome Projectnegative regulation of cell growth
GO:0030326
IGI
Genome Projectembryonic limb morphogenesis
GO:0030509
IDA, IGI
ISO
Genome ProjectBMP signaling pathway
GO:0030513
IGI
Genome Projectpositive regulation of BMP signaling pathway
GO:0030900
IMP
Genome Projectforebrain development
GO:0030901
IMP
Genome Projectmidbrain development
GO:0034504
ISO
IEA
Genome Projectprotein localization to nucleus
GO:0035115
IGI
Genome Projectembryonic forelimb morphogenesis
GO:0035116
IGI
Genome Projectembryonic hindlimb morphogenesis
GO:0035880
IMP, IGI
ISO
IEA
Genome Projectembryonic nail plate morphogenesis
GO:0042474
IMP
Genome Projectmiddle ear morphogenesis
GO:0042475
IMP
ISO
IEA
Genome Projectodontogenesis of dentin-containing tooth
GO:0042476
IMP, IGI
Genome Projectodontogenesis
GO:0042481
IGI
Genome Projectregulation of odontogenesis
GO:0042733
IGI
Genome Projectembryonic digit morphogenesis
GO:0043066
IGI
Genome Projectnegative regulation of apoptotic process
GO:0043392
IDA
Genome Projectnegative regulation of DNA binding
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IMP, IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048863
IGI
Genome Projectstem cell differentiation
GO:0050821
ISO
IEA
Genome Projectprotein stabilization
GO:0051154
IDA, IGI
Genome Projectnegative regulation of striated muscle cell differentiation
GO:0060021
IMP
Genome Projectpalate development
GO:0060325
IMP, IGI
ISO
IEA
Genome Projectface morphogenesis
GO:0060349
IMP, IGI
Genome Projectbone morphogenesis
GO:0060536
IMP
Genome Projectcartilage morphogenesis
GO:0061180
IGI
Genome Projectmammary gland epithelium development
GO:0061312
IGI
Genome ProjectBMP signaling pathway involved in heart development
GO:0090427
IGI
Genome Projectactivation of meiosis
GO:1902255
ISO
IEA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:2000678
IGI
Genome Projectnegative regulation of transcription regulatory region DNA binding
GO:2001055
IGI
Genome Projectpositive regulation of mesenchymal cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IMP
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000982
IDA
Genome Projecttranscription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001227
IDA, IMP
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0001228
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0002039
ISO
IEA
Genome Projectp53 binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IDA
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IGI
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site
IPR020479Homeodomain, metazoa

No MapMan annotations defined for this gene.