Gene: ENSMUSG00000047123 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000047123
Transcript Identifier
ENSMUST00000058136
Gene Type
Coding gene
Location
17 : 56269895-56272093 : negative

Family Information

Homologous gene family
HOM03P027111
(3 genes in 2 species)
specific family

Descriptions

gene_descr
toll-like receptor adaptor molecule 1

Identifiers

Type Value
UniprotQ80UF7
MGI2147032

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002281
IMP
Genome Projectmacrophage activation involved in immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002756
IMP
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0030890
IMP
Genome Projectpositive regulation of B cell proliferation
GO:0031398
IDA
Genome Projectpositive regulation of protein ubiquitination
GO:0031663
IMP
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032092
IDA
Genome Projectpositive regulation of protein binding
GO:0032481
IMP
Genome Projectpositive regulation of type I interferon production
GO:0032496
IMP, IGI
Genome Projectresponse to lipopolysaccharide
GO:0032755
IMP
Genome Projectpositive regulation of interleukin-6 production
GO:0032760
IDA, IMP, IGI
Genome Projectpositive regulation of tumor necrosis factor production
GO:0032816
IMP
Genome Projectpositive regulation of natural killer cell activation
GO:0043123
IMP, IGI
ISO
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330
IDA, IMP
ISO
IEA
Genome Projectresponse to exogenous dsRNA
GO:0043496
IMP
Genome Projectregulation of protein homodimerization activity
GO:0045080
IMP, IGI
Genome Projectpositive regulation of chemokine biosynthetic process
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045359
IMP
Genome Projectpositive regulation of interferon-beta biosynthetic process
GO:0045429
IMP
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0050871
IMP
Genome Projectpositive regulation of B cell activation
GO:0051092
IMP, IGI
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051607
IMP
IEA
Genome Projectdefense response to virus
GO:0097190
IMP
Genome Projectapoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
ISO
IEA
Genome Projectsignal transducer activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005776
IEA
Genome Projectautophagosome
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0097342
ISO
IEA
Genome Projectripoptosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000157Toll/interleukin-1 receptor homology (TIR) domain
IPR017278TIR domain-containing adapter molecule 1
IPR025735RHIM domain

No MapMan annotations defined for this gene.