Gene: ENSMUSG00000045730 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000045730
Transcript Identifier
ENSMUST00000053640
Gene Type
Coding gene
Location
18 : 62178496-62179752 : negative

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P062719
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
adrenergic receptor, beta 2

Identifiers

Type Value
UniprotP18762
MGI87938

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001889
IEA
Genome Projectliver development
GO:0001993
IMP
Genome Projectregulation of systemic arterial blood pressure by norepinephrine-epinephrine
GO:0002024
IGI
Genome Projectdiet induced thermogenesis
GO:0002025
IMP, IGI
IEA
Genome Projectvasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0002028
IMP
Genome Projectregulation of sodium ion transport
GO:0002032
ISS, ISO
IEA
Genome Projectdesensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002086
IEA
Genome Projectdiaphragm contraction
GO:0003059
IEA
Genome Projectpositive regulation of the force of heart contraction by epinephrine
GO:0006898
ISS, ISO
IEA
Genome Projectreceptor-mediated endocytosis
GO:0006940
IEA
Genome Projectregulation of smooth muscle contraction
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007189
IDA, IMP
IEA
Genome Projectadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190
ISS, ISO
IEA
Genome Projectactivation of adenylate cyclase activity
GO:0007267
IBA
Genome Projectcell-cell signaling
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0007568
IEA
Genome Projectaging
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008306
IEA
Genome Projectassociative learning
GO:0009409
IGI
Genome Projectresponse to cold
GO:0010765
IEA
Genome Projectpositive regulation of sodium ion transport
GO:0016525
IEA
Genome Projectnegative regulation of angiogenesis
GO:0030279
IEA
Genome Projectnegative regulation of ossification
GO:0030501
IMP
Genome Projectpositive regulation of bone mineralization
GO:0031398
ISO
IEA
Genome Projectpositive regulation of protein ubiquitination
GO:0031649
IGI
Genome Projectheat generation
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0032781
IEA
Genome Projectpositive regulation of ATPase activity
GO:0033574
IEA
Genome Projectresponse to testosterone
GO:0035249
IEA
Genome Projectsynaptic transmission, glutamatergic
GO:0035811
IEA
Genome Projectnegative regulation of urine volume
GO:0040015
IGI
Genome Projectnegative regulation of multicellular organism growth
GO:0042060
IEA
Genome Projectwound healing
GO:0042312
IEA
Genome Projectregulation of vasodilation
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043268
IEA
Genome Projectpositive regulation of potassium ion transport
GO:0043410
ISS, ISO
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0043627
IEA
Genome Projectresponse to estrogen
GO:0044849
IEA
Genome Projectestrous cycle
GO:0045453
IMP
Genome Projectbone resorption
GO:0045823
IEA
Genome Projectpositive regulation of heart contraction
GO:0045909
IEA
Genome Projectpositive regulation of vasodilation
GO:0045944
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0045986
IGI
Genome Projectnegative regulation of smooth muscle contraction
GO:0048633
IEA
Genome Projectpositive regulation of skeletal muscle tissue growth
GO:0050728
IEA
Genome Projectnegative regulation of inflammatory response
GO:0050873
IGI
Genome Projectbrown fat cell differentiation
GO:0051924
IEA
Genome Projectregulation of calcium ion transport
GO:0051930
IEA
Genome Projectregulation of sensory perception of pain
GO:0060079
IEA
Genome Projectexcitatory postsynaptic potential
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0071548
IEA
Genome Projectresponse to dexamethasone
GO:0071867
IEA
Genome Projectresponse to monoamine
GO:0071880
IBA
Genome Projectadenylate cyclase-activating adrenergic receptor signaling pathway
GO:0090331
IEA
Genome Projectnegative regulation of platelet aggregation
GO:0097421
IEA
Genome Projectliver regeneration
GO:0098779
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1903146
IEA
Genome Projectregulation of mitophagy

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001965
IEA
Genome ProjectG-protein alpha-subunit binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004935
IEA
Genome Projectadrenergic receptor activity
GO:0004941
IDA
ISO
IEA
Genome Projectbeta2-adrenergic receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008144
IEA
Genome Projectdrug binding
GO:0008179
IDA
Genome Projectadenylate cyclase binding
GO:0015459
ISO
IEA
Genome Projectpotassium channel regulator activity
GO:0019899
IPI
Genome Projectenzyme binding
GO:0031713
IEA
Genome ProjectB2 bradykinin receptor binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0035240
IEA
Genome Projectdopamine binding
GO:0035255
IEA
Genome Projectionotropic glutamate receptor binding
GO:0042803
ISS, ISO
IEA
Genome Projectprotein homodimerization activity
GO:0051379
IBA
Genome Projectepinephrine binding
GO:0051380
ISS, ISO
IEA
Genome Projectnorepinephrine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005886
ISO
TAS, IEA
Genome Projectplasma membrane
GO:0005887
ISO, IBA
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0032809
IEA
Genome Projectneuronal cell body membrane
GO:0042383
IEA
Genome Projectsarcolemma
GO:0043197
IEA
Genome Projectdendritic spine
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0043235
ISS, ISO
IEA
Genome Projectreceptor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000332Beta 2 adrenoceptor
IPR002233Adrenoceptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.