Gene: ENSMUSG00000045613 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000045613
Transcript Identifier
ENSMUST00000172278
Gene Type
Coding gene
Location
6 : 36523210-36524610 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024233
(4 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
cholinergic receptor, muscarinic 2, cardiac

Identifiers

Type Value
UniprotQ9ERZ4
MGI88397

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006940
IBA
IEA
Genome Projectregulation of smooth muscle contraction
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007197
IBA
Genome Projectadenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
GO:0007207
IBA
Genome Projectphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007213
IMP
ISS, ISO
IEA
Genome ProjectG-protein coupled acetylcholine receptor signaling pathway
GO:0007271
IBA
Genome Projectsynaptic transmission, cholinergic
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0008016
IBA
IEA
Genome Projectregulation of heart contraction
GO:0009615
IEA
Genome Projectresponse to virus
GO:0051482
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0008144
IEA
Genome Projectdrug binding
GO:0016907
IMP
ISS, ISO
IEA
Genome ProjectG-protein coupled acetylcholine receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005887
ISS, ISO, IBA
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0032279
IEA
Genome Projectasymmetric synapse
GO:0032280
IEA
Genome Projectsymmetric synapse
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0043679
IEA
Genome Projectaxon terminus
GO:0045202
IBA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000995Muscarinic acetylcholine receptor family
IPR001065Muscarinic acetylcholine receptor M2
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.