Gene: ENSMUSG00000045103 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000045103
Transcript Identifier
ENSMUST00000114000
Gene Type
Coding gene
Location
X : 82949117-85202482 : positive

Family Information

Homologous gene family
HOM03P000481
(99 genes in 11 species)
specific family

Descriptions

gene_descr
dystrophin, muscular dystrophy

Identifiers

Type Value
UniprotP11531
MGI94909

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001954
IMP
Genome Projectpositive regulation of cell-matrix adhesion
GO:0002027
IMP
ISO
Genome Projectregulation of heart rate
GO:0006355
IMP
Genome Projectregulation of transcription, DNA-templated
GO:0007517
IMP
Genome Projectmuscle organ development
GO:0007519
IMP, IGI
Genome Projectskeletal muscle tissue development
GO:0008065
IMP
Genome Projectestablishment of blood-nerve barrier
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010880
IMP
Genome Projectregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881
IMP
Genome Projectregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010976
ISO
Genome Projectpositive regulation of neuron projection development
GO:0014809
IMP
Genome Projectregulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0014819
IMP
Genome Projectregulation of skeletal muscle contraction
GO:0014904
IMP
Genome Projectmyotube cell development
GO:0016203
IEA
Genome Projectmuscle attachment
GO:0021629
IMP
Genome Projectolfactory nerve structural organization
GO:0033137
IMP
Genome Projectnegative regulation of peptidyl-serine phosphorylation
GO:0034613
IMP
ISO
Genome Projectcellular protein localization
GO:0035994
IMP
Genome Projectresponse to muscle stretch
GO:0042391
IMP
Genome Projectregulation of membrane potential
GO:0043043
ISO
Genome Projectpeptide biosynthetic process
GO:0043623
IMP
Genome Projectcellular protein complex assembly
GO:0045213
IMP
Genome Projectneurotransmitter receptor metabolic process
GO:0045666
ISO
Genome Projectpositive regulation of neuron differentiation
GO:0046716
IMP
Genome Projectmuscle cell cellular homeostasis
GO:0048747
IGI
Genome Projectmuscle fiber development
GO:0051647
IMP
Genome Projectnucleus localization
GO:0060048
ISO
Genome Projectcardiac muscle contraction
GO:0060314
IMP
Genome Projectregulation of ryanodine-sensitive calcium-release channel activity
GO:0060857
IMP
Genome Projectestablishment of glial blood-brain barrier
GO:0070373
IMP
Genome Projectnegative regulation of ERK1 and ERK2 cascade
GO:0086001
IMP
Genome Projectcardiac muscle cell action potential
GO:0090287
ISO
Genome Projectregulation of cellular response to growth factor stimulus
GO:1901385
IMP
Genome Projectregulation of voltage-gated calcium channel activity
GO:1902083
IMP
Genome Projectnegative regulation of peptidyl-cysteine S-nitrosylation
GO:2000651
IMP
Genome Projectpositive regulation of sodium ion transmembrane transporter activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002162
ISO
IEA
Genome Projectdystroglycan binding
GO:0003779
ISO
IEA
Genome Projectactin binding
GO:0005200
IEA
Genome Projectstructural constituent of cytoskeleton
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0008307
ISO
Genome Projectstructural constituent of muscle
GO:0017022
ISO
Genome Projectmyosin binding
GO:0017166
ISO
Genome Projectvinculin binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050998
IPI
Genome Projectnitric-oxide synthase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0016010
IDA
ISO
Genome Projectdystrophin-associated glycoprotein complex
GO:0016020
IEA
Genome Projectmembrane
GO:0030018
IDA
Genome ProjectZ disc
GO:0030054
IDA
IEA
Genome Projectcell junction
GO:0030055
IDA
Genome Projectcell-substrate junction
GO:0030175
ISO
Genome Projectfilopodium
GO:0031527
ISO
Genome Projectfilopodium membrane
GO:0042383
IDA
ISO
IEA
Genome Projectsarcolemma
GO:0043034
ISO
Genome Projectcostamere
GO:0043234
ISO
Genome Projectprotein complex
GO:0044306
IDA
Genome Projectneuron projection terminus
GO:0045121
IDA
Genome Projectmembrane raft
GO:0045202
IDA
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000433Zinc finger, ZZ-type
IPR001202WW domain
IPR001589Actinin-type actin-binding domain, conserved site
IPR001715Calponin homology domain
IPR002017Spectrin repeat
IPR011992EF-hand domain pair
IPR015153EF-hand domain, type 1
IPR015154EF-hand domain, type 2
IPR016344Dystrophin
IPR018159Spectrin/alpha-actinin

No MapMan annotations defined for this gene.