Gene: ENSMUSG00000045038 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000045038
Transcript Identifier
ENSMUST00000097274
Gene Type
Coding gene
Location
17 : 86168593-86654687 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P005549
(15 genes in 6 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
protein kinase C, epsilon

Identifiers

Type Value
UniprotP16054
MGI97599

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002281
IMP
Genome Projectmacrophage activation involved in immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007049
IEA
Genome Projectcell cycle
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007635
TAS
Genome Projectchemosensory behavior
GO:0010634
ISS, ISO
IEA
Genome Projectpositive regulation of epithelial cell migration
GO:0010763
IMP
Genome Projectpositive regulation of fibroblast migration
GO:0010811
IMP, IGI
Genome Projectpositive regulation of cell-substrate adhesion
GO:0016310
IEA
Genome Projectphosphorylation
GO:0018105
ISO
IEA
Genome Projectpeptidyl-serine phosphorylation
GO:0019216
IMP
Genome Projectregulation of lipid metabolic process
GO:0030838
IDA
Genome Projectpositive regulation of actin filament polymerization
GO:0031663
IMP
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032024
IMP
Genome Projectpositive regulation of insulin secretion
GO:0032230
IMP
Genome Projectpositive regulation of synaptic transmission, GABAergic
GO:0032467
ISS, ISO
IEA
Genome Projectpositive regulation of cytokinesis
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0035641
IGI
Genome Projectlocomotory exploration behavior
GO:0035669
IMP
Genome ProjectTRAM-dependent toll-like receptor 4 signaling pathway
GO:0043085
ISO
IEA
Genome Projectpositive regulation of catalytic activity
GO:0043123
IMP
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278
IMP
Genome Projectresponse to morphine
GO:0043410
IDA, IMP
Genome Projectpositive regulation of MAPK cascade
GO:0050730
IMP
Genome Projectregulation of peptidyl-tyrosine phosphorylation
GO:0050996
IMP
Genome Projectpositive regulation of lipid catabolic process
GO:0051209
IMP
Genome Projectrelease of sequestered calcium ion into cytosol
GO:0051279
IDA
Genome Projectregulation of release of sequestered calcium ion into cytosol
GO:0051301
IEA
Genome Projectcell division
GO:0061178
IMP
Genome Projectregulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070257
IMP
Genome Projectpositive regulation of mucus secretion
GO:0071361
IGI
Genome Projectcellular response to ethanol
GO:0071380
IDA
Genome Projectcellular response to prostaglandin E stimulus
GO:0071456
IDA
Genome Projectcellular response to hypoxia
GO:0090303
ISS, ISO
IEA
Genome Projectpositive regulation of wound healing
GO:2000273
IDA
Genome Projectpositive regulation of receptor activity
GO:2001031
ISO
IEA
Genome Projectpositive regulation of cellular glucuronidation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003785
IDA
Genome Projectactin monomer binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA
ISO
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
ISO
IEA
Genome Projectprotein kinase C activity
GO:0004699
IDA
IEA
Genome Projectcalcium-independent protein kinase C activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008047
ISO
IEA
Genome Projectenzyme activator activity
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0030546
IDA
Genome Projectreceptor activator activity
GO:0035276
IDA
Genome Projectethanol binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0071889
IPI
Genome Project14-3-3 protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0005783
ISO
IEA
Genome Projectendoplasmic reticulum
GO:0005829
IDA
ISO
IEA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0048471
IDA
IEA
Genome Projectperinuclear region of cytoplasm
GO:0071944
IDA
Genome Projectcell periphery
GO:0005794
IDA
Genome ProjectGolgi apparatus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR014376Protein kinase C, delta/epsilon/eta/theta types
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal
IPR020454Diacylglycerol/phorbol-ester binding
IPR027274Protein kinase C, epsilon

No MapMan annotations defined for this gene.