Gene: ENSMUSG00000042406 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000042406
Transcript Identifier
ENSMUST00000109605
Gene Type
Coding gene
Location
15 : 80256299-80257460 : positive

Family Information

Homologous gene family
HOM03P030373
(3 genes in 3 species)
specific family

Descriptions

gene_descr
activating transcription factor 4

Identifiers

Type Value
UniprotQ06507
MGI88096

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006094
IDA
Genome Projectgluconeogenesis
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA, IMP
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IDA
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IMP
Genome Projecttranscription from RNA polymerase II promoter
GO:0007214
IEA
Genome Projectgamma-aminobutyric acid signaling pathway
GO:0007623
IEP
Genome Projectcircadian rhythm
GO:0010575
ISO
IEA
Genome Projectpositive regulation of vascular endothelial growth factor production
GO:0010628
IMP
ISO
Genome Projectpositive regulation of gene expression
GO:0032922
IMP
Genome Projectcircadian regulation of gene expression
GO:0034198
IMP
Genome Projectcellular response to amino acid starvation
GO:0034976
IDA
ISO
IEA
Genome Projectresponse to endoplasmic reticulum stress
GO:0036091
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0036499
IMP
Genome ProjectPERK-mediated unfolded protein response
GO:0042149
ISO
IEA
Genome Projectcellular response to glucose starvation
GO:0043267
IEA
Genome Projectnegative regulation of potassium ion transport
GO:0043525
IMP
Genome Projectpositive regulation of neuron apoptotic process
GO:0045893
IDA
ISS, ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045943
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase I promoter
GO:0045944
IDA, IMP, IGI
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048511
IEA
Genome Projectrhythmic process
GO:0070059
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1903204
ISO
IEA
Genome Projectnegative regulation of oxidative stress-induced neuron death
GO:1990440
IMP
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IMP
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981
ISO
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0001077
IMP
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085
ISO
IEA
Genome ProjectRNA polymerase II transcription factor binding
GO:0003677
IDA, IGI
ISO
IEA
Genome ProjectDNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IEA
Genome Projectprotein C-terminus binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0043522
ISO
IEA
Genome Projectleucine zipper domain binding
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
NAS
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005815
IEA
Genome Projectmicrotubule organizing center
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0032590
IEA
Genome Projectdendrite membrane
GO:0034399
ISO
IEA
Genome Projectnuclear periphery
GO:0043005
ISO
IEA
Genome Projectneuron projection
GO:1990037
ISO
IEA
Genome ProjectLewy body core
GO:1990589
IDA
ISO
IEA
Genome ProjectATF4-CREB1 transcription factor complex
GO:1990590
IDA
ISO
IEA
Genome ProjectATF1-ATF4 transcription factor complex
GO:1990617
ISO
IEA
Genome ProjectCHOP-ATF4 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004827Basic-leucine zipper domain
IPR029811cAMP-dependent transcription factor ATF-4

No MapMan annotations defined for this gene.