Gene: ENSMUSG00000042284 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000042284
Transcript Identifier
ENSMUST00000061673
Gene Type
Coding gene
Location
13 : 114960090-115101531 : negative

Family Information

Homologous gene family
HOM03P002672
(35 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P017077
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
integrin alpha 1

Identifiers

Type Value
UniprotQ3V3R4
MGI96599

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IEA
Genome Projectactivation of MAPK activity
GO:0007155
IMP
IEA
Genome Projectcell adhesion
GO:0007160
ISO
IEA
Genome Projectcell-matrix adhesion
GO:0007229
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0008285
ISS, ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0030593
IMP
Genome Projectneutrophil chemotaxis
GO:0032516
ISS, ISO
IEA
Genome Projectpositive regulation of phosphoprotein phosphatase activity
GO:0042059
IMP
Genome Projectnegative regulation of epidermal growth factor receptor signaling pathway
GO:0042311
IEA
Genome Projectvasodilation
GO:0043525
IEA
Genome Projectpositive regulation of neuron apoptotic process
GO:0045123
IMP
Genome Projectcellular extravasation
GO:0048812
IEA
Genome Projectneuron projection morphogenesis
GO:0060326
IEA
Genome Projectcell chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005518
IEA
Genome Projectcollagen binding
GO:0019903
ISO
IEA
Genome Projectprotein phosphatase binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0098639
ISO
IEA
Genome Projectcollagen binding involved in cell-matrix adhesion

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001669
IEA
Genome Projectacrosomal vesicle
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0008305
IEA
Genome Projectintegrin complex
GO:0009897
IDA
IEA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
ISO
IEA
Genome Projectcell surface
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0034665
ISO
IEA
Genome Projectintegrin alpha1-beta1 complex
GO:0043005
IEA
Genome Projectneuron projection
GO:0043204
IEA
Genome Projectperikaryon
GO:0045121
IEA
Genome Projectmembrane raft
GO:0045178
IDA
Genome Projectbasal part of cell
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000413Integrin alpha chain
IPR002035von Willebrand factor, type A
IPR013517FG-GAP repeat
IPR013519Integrin alpha beta-propellor
IPR013649Integrin alpha-2
IPR018184Integrin alpha chain, C-terminal cytoplasmic region, conserved site

No MapMan annotations defined for this gene.