Gene: ENSMUSG00000041498 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000041498
Transcript Identifier
ENSMUST00000189413
Gene Type
Coding gene
Location
1 : 136467958-136527616 : positive

Family Information

Homologous gene family
HOM03P000016
(1236 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P065785
(2 genes in 2 species)
specific family

Descriptions

gene_descr
kinesin family member 14

Identifiers

Type Value
UniprotL0N7N1
MGI1098226

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001558
ISS, ISO
IEA
Genome Projectregulation of cell growth
GO:0007018
IBA
IEA
Genome Projectmicrotubule-based movement
GO:0007080
ISS, ISO
IEA
Genome Projectmitotic metaphase plate congression
GO:0008284
ISS, ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010389
ISS, ISO
IEA
Genome Projectregulation of G2/M transition of mitotic cell cycle
GO:0021685
IMP
Genome Projectcerebellar granular layer structural organization
GO:0021693
IMP
Genome Projectcerebellar Purkinje cell layer structural organization
GO:0021695
IMP
Genome Projectcerebellar cortex development
GO:0021766
IMP
Genome Projecthippocampus development
GO:0021772
IMP
Genome Projectolfactory bulb development
GO:0021846
IMP
Genome Projectcell proliferation in forebrain
GO:0021987
IMP
Genome Projectcerebral cortex development
GO:0030155
ISO
IEA
Genome Projectregulation of cell adhesion
GO:0030334
ISO
IEA
Genome Projectregulation of cell migration
GO:0030705
IBA
Genome Projectcytoskeleton-dependent intracellular transport
GO:0031146
ISS, ISO
IEA
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031641
IMP
Genome Projectregulation of myelination
GO:0032147
ISS, ISO
IEA
Genome Projectactivation of protein kinase activity
GO:0032467
ISS, ISO
IEA
Genome Projectpositive regulation of cytokinesis
GO:0032487
ISO
IEA
Genome Projectregulation of Rap protein signal transduction
GO:0033624
ISO
IEA
Genome Projectnegative regulation of integrin activation
GO:0034446
ISO
IEA
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0043066
ISS, ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043161
ISS, ISO
IEA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043523
IMP
Genome Projectregulation of neuron apoptotic process
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0045184
ISO
IEA
Genome Projectestablishment of protein localization
GO:0051301
IMP
Genome Projectcell division
GO:1903047
ISS, ISO
IEA
Genome Projectmitotic cell cycle process
GO:1903429
IMP
Genome Projectregulation of cell maturation
GO:2000045
ISS, ISO
IEA
Genome Projectregulation of G1/S transition of mitotic cell cycle
GO:0007019
IDA
Genome Projectmicrotubule depolymerization
GO:1902519
ISS
Genome Projectresponse to docetaxel trihydrate

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003777
IEA
Genome Projectmicrotubule motor activity
GO:0005524
IDA
IEA
Genome ProjectATP binding
GO:0008017
IDA
IEA
Genome Projectmicrotubule binding
GO:0008574
IDA
Genome ProjectATP-dependent microtubule motor activity, plus-end-directed
GO:0015631
IDA
Genome Projecttubulin binding
GO:0016887
IDA
Genome ProjectATPase activity
GO:0019901
ISO
IEA
Genome Projectprotein kinase binding
GO:0030165
ISO
IEA
Genome ProjectPDZ domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005819
IEA
Genome Projectspindle
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005871
IBA
IEA
Genome Projectkinesin complex
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0005886
ISS, ISO
IEA
Genome Projectplasma membrane
GO:0016020
ISS, ISO
IEA
Genome Projectmembrane
GO:0030496
ISS, ISO
IEA
Genome Projectmidbody
GO:0051233
ISS, ISO
IEA
Genome Projectspindle midzone

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000253Forkhead-associated (FHA) domain
IPR001752Kinesin motor domain
IPR008984SMAD/FHA domain
IPR019821Kinesin motor domain, conserved site
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR027640Kinesin-like protein
IPR032405Kinesin-associated

No MapMan annotations defined for this gene.