Gene: ENSMUSG00000041415 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000041415
Transcript Identifier
ENSMUST00000041987
Gene Type
Coding gene
Location
12 : 104691593-104731913 : negative

Family Information

Homologous gene family
HOM03P000904
(66 genes in 21 species)
specific family
Orthologous gene family
ORTHO03P027247
(4 genes in 4 species)
specific family

Descriptions

gene_descr
dicer 1, ribonuclease type III

Identifiers

Type Value
UniprotF8VQ54
MGI2177178

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IMP
Genome Projectangiogenesis
GO:0001942
IMP
Genome Projecthair follicle development
GO:0006309
IBA
Genome Projectapoptotic DNA fragmentation
GO:0006396
IDA, IMP
IEA
Genome ProjectRNA processing
GO:0008283
IMP
Genome Projectcell proliferation
GO:0009791
IMP
Genome Projectpost-embryonic development
GO:0010070
IMP
Genome Projectzygote asymmetric cell division
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0010660
IMP
Genome Projectregulation of muscle cell apoptotic process
GO:0014835
IMP
Genome Projectmyoblast differentiation involved in skeletal muscle regeneration
GO:0016075
IEA
Genome ProjectrRNA catabolic process
GO:0019827
IMP
Genome Projectstem cell population maintenance
GO:0021522
IMP
Genome Projectspinal cord motor neuron differentiation
GO:0021889
IMP
Genome Projectolfactory bulb interneuron differentiation
GO:0021987
IMP
Genome Projectcerebral cortex development
GO:0030324
IMP
Genome Projectlung development
GO:0030326
IMP
Genome Projectembryonic limb morphogenesis
GO:0030422
IDA
ISO
IEA
Genome Projectproduction of siRNA involved in RNA interference
GO:0030423
ISO
IEA
Genome Projecttargeting of mRNA for destruction involved in RNA interference
GO:0031054
IDA
ISO
IEA
Genome Projectpre-miRNA processing
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0031641
IMP
Genome Projectregulation of myelination
GO:0031643
IMP
Genome Projectpositive regulation of myelination
GO:0033168
ISO
IEA
Genome Projectconversion of ds siRNA to ss siRNA involved in RNA interference
GO:0035087
ISO
Genome ProjectsiRNA loading onto RISC involved in RNA interference
GO:0035116
IMP
Genome Projectembryonic hindlimb morphogenesis
GO:0035196
IMP
ISO
Genome Projectproduction of miRNAs involved in gene silencing by miRNA
GO:0035264
IMP
Genome Projectmulticellular organism growth
GO:0035280
ISO
IEA
Genome ProjectmiRNA loading onto RISC involved in gene silencing by miRNA
GO:0036404
ISO
IEA
Genome Projectconversion of ds siRNA to ss siRNA
GO:0042487
IMP
Genome Projectregulation of odontogenesis of dentin-containing tooth
GO:0045069
IMP
Genome Projectregulation of viral genome replication
GO:0045595
IMP
Genome Projectregulation of cell differentiation
GO:0045664
IMP
Genome Projectregulation of neuron differentiation
GO:0048255
IMP
Genome ProjectmRNA stabilization
GO:0048536
IMP
Genome Projectspleen development
GO:0048565
IMP
Genome Projectdigestive tract development
GO:0048608
IMP
Genome Projectreproductive structure development
GO:0048713
IMP
Genome Projectregulation of oligodendrocyte differentiation
GO:0048730
IMP
Genome Projectepidermis morphogenesis
GO:0048754
IMP
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048856
IMP
Genome Projectanatomical structure development
GO:0050767
IMP
Genome Projectregulation of neurogenesis
GO:0051216
IMP
Genome Projectcartilage development
GO:0051225
IMP
Genome Projectspindle assembly
GO:0051252
IMP
Genome Projectregulation of RNA metabolic process
GO:0051607
IMP
Genome Projectdefense response to virus
GO:0051726
IMP
Genome Projectregulation of cell cycle
GO:0055013
IMP
Genome Projectcardiac muscle cell development
GO:0060119
IMP
Genome Projectinner ear receptor cell development
GO:0060253
IMP
Genome Projectnegative regulation of glial cell proliferation
GO:0060576
IGI
Genome Projectintestinal epithelial cell development
GO:0061309
IMP
Genome Projectcardiac neural crest cell development involved in outflow tract morphogenesis
GO:0061548
IMP
Genome Projectganglion development
GO:0070173
IMP
Genome Projectregulation of enamel mineralization
GO:0071335
IMP
Genome Projecthair follicle cell proliferation
GO:0090501
IBA
Genome ProjectRNA phosphodiester bond hydrolysis
GO:0090502
ISO
IEA
Genome ProjectRNA phosphodiester bond hydrolysis, endonucleolytic
GO:2000628
IMP
Genome Projectregulation of miRNA metabolic process
GO:2000630
IMP
Genome Projectpositive regulation of miRNA metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003725
ISO
IEA
Genome Projectdouble-stranded RNA binding
GO:0004386
IEA
Genome Projecthelicase activity
GO:0004521
ISO
IEA
Genome Projectendoribonuclease activity
GO:0004525
IDA
ISO, ISA
IEA
Genome Projectribonuclease III activity
GO:0004530
IBA
Genome Projectdeoxyribonuclease I activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016891
IEA
Genome Projectendoribonuclease activity, producing 5'-phosphomonoesters
GO:0019904
ISO
Genome Projectprotein domain specific binding
GO:0035197
ISO
Genome ProjectsiRNA binding
GO:0035198
IDA
Genome ProjectmiRNA binding
GO:0070883
ISO
IEA
Genome Projectpre-miRNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005793
IEA
Genome Projectendoplasmic reticulum-Golgi intermediate compartment
GO:0016442
IBA
IEA
Genome ProjectRISC complex
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0030426
IEA
Genome Projectgrowth cone
GO:0035068
IDA
Genome Projectmicro-ribonucleoprotein complex
GO:0070578
ISO
IEA
Genome ProjectRISC-loading complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000999Ribonuclease III domain
IPR001650Helicase, C-terminal
IPR003100PAZ domain
IPR005034Dicer dimerisation domain
IPR006935Helicase/UvrB, N-terminal
IPR011907Ribonuclease III
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR014720Double-stranded RNA-binding domain
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.